[G—^3H]—雷公藤甲素的制备  

Preparation of[G-3 H]-Triptolid

作　　者：武德柱[1] 高巍[1] 

机构地区：[1]中国原子能科学研究院同位素研究所,北京102413

出　　处：《核化学与放射化学》2002年第3期187-188,192,共3页Journal of Nuclear and Radiochemistry

摘　　要：采用催化气 液同位素交换法制备了氚化雷公藤甲素 ,探讨了反应时间和反应介质对反应产额的影响。用纸色层法分离与纯化产品 ,最终获得产品的放射性比活度和放化纯度分别为 0 6 1TBq/g和 98%。The catalytic gas liquid isotope exchange reaction is a good method to prepare tritiated triptolid. The optimum reaction time and solvent are selected to the reaction system and the paper chromatography is used to separate and purify the product. The specific activity and radiochemical purity of the final product obtained are 0.61 TBq/g and 98%, respectively.

关 键 词：催化气-液同位素交换法 雷公藤甲素 氚化雷公藤甲素 氚标记 中草药 

分 类 号：R817.9[医药卫生—影像医学与核医学]