老年糖尿病人甲襞微循环改变与眼底血流动力学变化  

Microcirculation and fundus oculi hemodynamics in senile patients with diabetes mellitus

作　　者：任斌[1] 李瑜乐[1] 姜学忠[1] 戎娟[1] 

机构地区：[1]江苏省老年医院,南京市210024

出　　处：《实用老年医学》2002年第5期250-251,共2页Practical Geriatrics

摘　　要：目的　观察老年 2型糖尿病 (2DM)病人甲襞微循环改变及眼底动脉血流动力学变化并探讨其临床意义。　 方法 　对 40例老年 2DM病人 (DM组 )及 3 0例健康老年人 (对照组 )行甲襞微循环观测并用彩色多普勒超声显像 (CDFI)检测其双眼底动脉血流动力学变化。　 结果 　DM组的管袢变细 ,畸形增多 ,其数目、形态、血液流态及袢周状态的分值及总积分明显高于对照组 ,而血液流速显著低于对照组 (P <0 0 1) ;DM组眼底血流的脉搏指数 (PI)及阻力指数 (RI)高于对照组 (P <0 0 1)。　 结论　老年DM病人微循环明显障碍 ,可作为诊治其并发症及判断疗效的筛选指标 ;老年DM病人眼底血流PI及RI与眼底病变有极高相关性 ,可作为早期发现眼底微血管病的一种可靠方法。Objective To investigate the changes of microcirculation and fundus oculi hemodynamics in senile patients with diabetes mellitus(DM). Methods The changes in the nailfold microcirculation were observed and the hemodynamics of ophthalmic arteries(OA)and central retinal arteries(CRA)were studied with CDFI in 40 patients with DM and 30 healthy subjects. Results The abnormal vascular loops were increased and the velocity was slowed in patients and the integral value of each and total index of nailfold microcirculation were obviously higher than those of the control group( P <0 01);both resistance index and pulsatile index increased significantly( P <0 01). Conclusions The microcirculation and hemodynamics of fundus oculi artery in patients with DM were significantly changed and may be markers in diagnosis and prognosis.

关 键 词：糖尿病 甲襞微循环 彩色多普勒超声显像 眼底动脉 血流动力学 老年人 

分 类 号：R587.1[医药卫生—内分泌]