针刺对脑梗塞患者脑内葡萄糖代谢的影响  

Influence of Acupuncture on Cerebral Glucose Metabolism in Patients with Cerebral Infarction

作　　者：李霁[1] 左传涛[1] 管一晖[1] 赵军[1] 董竞成[1] 

机构地区：[1]复旦大学附属华山医院,上海200040

出　　处：《中国中西医结合杂志》2002年第10期741-744,共4页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的 :观察电针负荷时 11例脑梗塞患者局部脑葡萄糖代谢和脑细胞功能的变化 ,研究针刺治疗脑梗塞的穴位对脑梗塞的作用机制 ,及针刺这些穴位对脑功能区影响的位置。方法 :选穴为合谷与曲池 ,足三里和上巨虚 ,三阴交 ,选肢体瘫痪侧取穴。另加头部运动区和风池 (对应于肢体取穴的一侧 )。应用正电子发射型计算机断层显像 (简称PET)技术观察脑局部葡萄糖代谢。结果 :针刺穴位后 ,提示脑梗塞患者病灶侧的中、侧额叶 ,上颞叶 ,顶叶和丘脑 ,及双侧下额叶、中颞叶、脑岛放射性增高为主 ,病变脑区和正常脑区都有反应 ,病变脑区相对于其正常脑区反应敏感。结论 :PET影像技术非常适合研究针刺对脑梗塞的作用机制 ,且进一步说明了针刺调节作用具有整体性和双向性的特点。Objective: To observe the changes of regional cerebral glucose metabolism and brain cell function in patients with cerebral infarction for investigating the mechanism of effect of acupuncture in treating cerebral infarction and the affected position. Methods: Acupoints, including Hegu, Quchi, Zusanli, Shangjuxu, Sanyinjiao (in the paralysed side) and Fengchi (of the unilateral side) as well as the motion area of scalp acupunture, were selected for applying electric acupuncture. The regional glucose metabolism in brain was observed using positron emission computerized tomographic technique (PET). Results: PET showed that after acupuncture, the cerebral glucose metabolism and cerebral function activity increased mainly in lateral middle frontal lobe, superior temporal lobe, parietal lobe, thalamus of cerebral lesion of affected side, and bilateral inferior frontal lobe, middle temporal lobe and insula. Response to acupuncture revealed in brain of both sides, but the diseased side was more sensitive than that of normal side. Conclusion: PET is very fitting to studying mechanism of acupuncture on cerebral infarction. The regulatory effect of acupuncture has the characteristics of holism and bi directional regulation.

关 键 词：正电子发射型计算机断层显像 脑局部葡萄糖代谢 电针 脑梗塞 

分 类 号：R246.6[医药卫生—针灸推拿学]