吸附转移溶出伏安法测定氟罗沙星注射液含量  

Adsorptive transfer stripping voltammetric determination of fleroxacin

作　　者：缪谦[1] 程雅倩[1] 项光其[1] 何道法[1] 

机构地区：[1]温州师范学院化学与材料科学系,浙江温州325027

出　　处：《化学研究与应用》2002年第5期593-595,共3页Chemical Research and Application

摘　　要：A new,simple and convenient method was proposed to determine FLRX.Cyclic voltammetric behavior of Fleroxacin(FLRX) on graphite electrode was studied.FLRX can be strongly adsorbed on graphite electrode.At the potential of +1.040V(vs.SCE),FLRX is oxidized and adsorbed on the electrode surface.Using HAc～NaAc as a buffer solution, FLRX showed a reduction wave and the peak potential of -0.110V(vs.SCE) by linear sweep voltammetry after the electrode was washed by double distilled water.A new method for the determination of FLRX was established by adsorptive transfer stripping voltammetry.The peak current is proportional to the concentration of fleroxacin in the range of 4～42 μ g/mL.The method is simple,sensitive,fairly free of interference and accurate.A new,simple and convenient method was proposed to determine FLRX.Cyclic voltammetric behavior of Fleroxacin(FLRX) on graphite electrode was studied.FLRX can be strongly adsorbed on graphite electrode.At the potential of +1.040V(vs.SCE),FLRX is oxidized and adsorbed on the electrode surface.Using HAc～NaAc as a buffer solution, FLRX showed a reduction wave and the peak potential of -0.110V(vs.SCE) by linear sweep voltammetry after the electrode was washed by double distilled water.A new method for the determination of FLRX was established by adsorptive transfer stripping voltammetry.The peak current is proportional to the concentration of fleroxacin in the range of 4～42 μ g/mL.The method is simple,sensitive,fairly free of interference and accurate.

关 键 词：测定 氟罗沙星注射液 吸附转移溶出伏安法 石墨电极 抗菌药 药物含量 

分 类 号：R978.1[医药卫生—药品] R927.2[医药卫生—药学]