不同产地赤芍的FTIR指纹图谱对比分析  

Contrast analysis of FTIR fingerprints of Radix Paeoniae Rubra from different areas

作　　者：周红涛[1] 胡世林[1] 冯学锋[1] 杨京玉[1] 孙素琴[2] 

机构地区：[1]中国中医研究院中药研究所,北京100700 [2]清华大学化学系,北京100084

出　　处：《中草药》2002年第9期834-837,共4页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金重点资助课题 ( 39730 5 0 0 )

摘　　要：目的　寻找能够鉴别不同产地赤芍成分差异的新方法 ,探讨赤芍道地性的形成原因。方法　利用傅里叶变换红外光谱仪测定不同产地的样品 ,对所获得的指纹图谱进行特征峰指认和对比分析。结果　赤芍野生品与栽培品的红外吸收频率、吸收峰的相对强度都存在比较大的差异。多伦赤芍 (道地药材 )的红外吸收峰形状也有一定的特异性。结论　首次运用傅里叶变换红外光谱技术对不同产地芍药根部的混合化学体系进行了全组分快速分析 ,为赤芍道地商品的鉴别及质量控制提供了可靠的依据。Object To develop a new method of discriminating the principle components of Radix Paeoniae Rubra (RPR) from different areas, and to find the reason for forming high-quality of RPR in the place of the genuine. Methods Using Foruier transform infrared (FTIR) absorption spectrometry, the characteristic peaks of fingerprint infrared spectra of RPR samples from 18 habitats were recognized and compared. Results Frequency, intensity and shape of infrared absorption spectra were obviously different between wild and cultivated groups of RPR. The infrared absorption peaks of RPR in Duolun, a famous Chinese orthodox drug, were of distinct characteristics. Conclusion FTIR technique is first applied to rapid analysis of principle component of RPR from different areas. So an operable method in the quality control and discrimination of RPR in the place of the genuine is provided.

关 键 词：产地 FTIR 赤芍 傅里叶变换红外技术 指纹图谱 道地性 

分 类 号：R282.71[医药卫生—中药学] R282.5[医药卫生—中医学]