Feeding Supplemental lodine to Adult Mink;Effect on Thyroid Hormones in Adult and offspring  

Feeding Supplemental Iodine to Adult Mink; Effect on Thyroid Hormones in Adult and offspring^1

作　　者：RossE.JONES RICHARDJ.AULERICH ROBERTK.RINGER 

机构地区：[1]Texas,Michigan,Professor Instruments,m/s 81 P.O.Box655012,Dallas,TX 75265,State University Department of Animal Science,East Lansing,MI 48824,Emeritus Michigan State University,East Lansing,MI 48823,USA

出　　处：《Biomedical and Environmental Sciences》1993年第1期81-88,共8页生物医学与环境科学（英文版）

基　　金：Supported in part by the Mink Farmers Research Foundation,Thiensville,WI and The Heger Company,North St.Paul,MN.

摘　　要：We fed adult mink diets containing supplemental iodine, from 0 to 320 ppm, for one or seven months prior to breeding. Blood samples collected from the adults and their offspring (kits) at 4 wk post-partum were assayed for total thyroxine (T4), triiodothyronine (T3), reverse T3 (rT3), and T4-binding indices. As expected T4 concentrations of the adult and kit mink varied inversely with the level of supplemental iodine. In addition, T3 and rT3 concentrations decreased gradually in kits from the long-term experiment in response to the increased dietary iodine of the dams. T3 concentrations of kits from dams fed iodine short-term decreased markedly while rTy concentrations were elevated greatly in response to increased dietary iodine of the dam. These decreases in hormone levels are due to serum iodine blocking the thyroid uptake of iodine and subsequent decrease of hormone synthesis. Excess iodine may also block the effect of thyroid stimulating hormone. The T4-binding indices of the adults, in general, were depressed, while the T4-binding indices of the kits were more variable. These effects are probably due to fluctuations in thyroglobulin.We fed adult mink diets containing supplemental iodine, from 0 to 320 ppm, for one or seven months prior to breeding. Blood samples collected from the adults and their offspring (kits) at 4 wk post-partum were assayed for total thyroxine (T4), triiodothyronine (T3), reverse T3 (rT3), and T4-binding indices. As expected T4 concentrations of the adult and kit mink varied inversely with the level of supplemental iodine. In addition, T3 and rT3 concentrations decreased gradually in kits from the long-term experiment in response to the increased dietary iodine of the dams. T3 concentrations of kits from dams fed iodine short-term decreased markedly while rTy concentrations were elevated greatly in response to increased dietary iodine of the dam. These decreases in hormone levels are due to serum iodine blocking the thyroid uptake of iodine and subsequent decrease of hormone synthesis. Excess iodine may also block the effect of thyroid stimulating hormone. The T4-binding indices of the adults, in general, were depressed, while the T4-binding indices of the kits were more variable. These effects are probably due to fluctuations in thyroglobulin.

关 键 词：Feeding Supplemental lodine to Adult Mink Effect on Thyroid Hormones in Adult and offspring 

分 类 号：S865.22[农业科学—野生动物驯养]