Morphogenetic Action of Neurotransmitters on Regenerating Planarians—A Review  

作　　者：DAVIDVILLAR DAVIDJ.SCHAEFFER 

机构地区：[1]Department,Department of Veterinary Biosciences,University of Illinois 2001,South Lincoln Ave,Urbana IL 61801,USA,of Veterinary Biosciences,University of Illinois 2001,South Lincoln Ave,Urbana IL 61801,USA

出　　处：《Biomedical and Environmental Sciences》1993年第4期327-347,共21页生物医学与环境科学（英文版）

摘　　要：Planarians can be used as invertebrate bioassays to evaluate the role of neurotransmitters on regenerating cells. The influence of the nervous system is crucial to regenerate a normal complete animal. The neurotrophic action of the nervous system has been attributed to the major neurohormones present throughout the animal kingdom. The same type of transmitters found in mammals have been extensively found in many invertebrates, including planarians, but their role in regeneration is unclear. Neurotransmitters and drugs which act on neurohumoral transmission have been used to determine the role of each neurohormonc on regenerating planarians. Biochemical and pharmacological mechanisms of neurohormones on regenerative planarians are reviewed, as is their putative role on regeneration. Correlations with the roles of neurotransmitters in the central nervous system of higher organisms are also addressed.Planarians can be used as invertebrate bioassays to evaluate the role of neurotransmitters on regenerating cells. The influence of the nervous system is crucial to regenerate a normal complete animal. The neurotrophic action of the nervous system has been attributed to the major neurohormones present throughout the animal kingdom. The same type of transmitters found in mammals have been extensively found in many invertebrates, including planarians, but their role in regeneration is unclear. Neurotransmitters and drugs which act on neurohumoral transmission have been used to determine the role of each neurohormonc on regenerating planarians. Biochemical and pharmacological mechanisms of neurohormones on regenerative planarians are reviewed, as is their putative role on regeneration. Correlations with the roles of neurotransmitters in the central nervous system of higher organisms are also addressed.

关 键 词：Morphogenetic Action of Neurotransmitters on Regenerating Planarians A Review 

分 类 号：Q418[生物学—生理学] Q42