莫西沙星——一种新的氟喹诺酮类药物  

Moxifloxacino a New Fluoroguinolone Drug

作　　者：张英[1] 赵志刚[1] 张杰[1] 

机构地区：[1]北京天坛医院,北京100050

出　　处：《中国临床药理学杂志》2002年第5期396-400,共5页The Chinese Journal of Clinical Pharmacology

摘　　要：莫西沙星（商品名:拜复乐）是一种新的氟喹诺酮类药物,具有适当的较广的抗菌谱;保持较低水平的细菌耐药性;在感染关键部位可获得较高的药物浓度;每日用药一次;与其他药物的相互作用少或没有,不良反应低,特别是光毒性、肝脏或中枢神经系统反应较少。Moxifloxacin is a new fluoroguinolone,possesses all of these characteristics:have an appropriate breadth of antibacterial activity;maintain a low level of bacterial resistance;achieve high concentrations at key sites of infection; be dosed once (preferably) or twice a day;have few or no interactions with other drugs;have few or no adverse side-dffects,particularly phototoxicity, hepatic or CNS effects.

关 键 词：莫西沙星 氟喹诺酮类药物 抗菌活性 结构特点 

分 类 号：R978.19[医药卫生—药品]