高、低压舱致豚鼠耳气压损伤的形态学变化  

A comparative study on morphological changes of otic barotraumas of guinea pigs induced by hyperbaric and hypobaric chamber examination

作　　者：王玎[1] 王彭[1] 孙进军[1] 王绪锐[1] 杨宁江[2] 孙国华 

机构地区：[1]中国人民解放军第461医院耳鼻咽喉科,长春130021 [2]中国人民解放军第465医院,吉林132011 [3]空军兴城疗养院,辽宁兴城125100

出　　处：《中华航空航天医学杂志》2002年第3期166-168,F004,共4页Chinese Journal of Aerospace Medicine

摘　　要：目的　验证高压氧舱法和低压舱法检测咽鼓管通气功能时 ,引起实验豚鼠的中耳、内耳病理改变的一致性。　方法　健康的杂色豚鼠 36只随机分为 3个高压氧舱组和 3个低压舱组 ,分别在相应条件下进行模拟上升和下降实验 ,出舱电耳镜观察豚鼠鼓膜后处死 ,进行中耳及内耳组织学观察。　结果　鼓膜反应及中耳、内耳组织学改变组间无差异。Objective To compare the pathological changes of middle ear and inner ear of guinea pigs induced by hyperbaric and hypobaric chamber examinations for ventilation function of middle ear. Methods Thirty six guinea pigs served as subjects. They were randomly divided into 3 hyperbaric chamber groups and 3 hypobaric chamber groups. Three corresponding ascending and descending profiles of examination were used, and the state of tympanic membrane was observed following the examination. After that, animals were killed for microscopic examination of middle and inner ear. Results The congestion state of tympanic membrane and the morphological changes of middle ear and inner ear following examination in hyperbaric camber and hypobaric chamber were essentially the same. Conclusion Morphological observation confirmed that ventilation function of eustachian tube can be detected in hyperbaric chamber as well as in hypobaric chamber.

关 键 词：高压氧舱 低压舱 豚鼠 耳气压损伤 形态学变化 

分 类 号：R85[医药卫生—航空、航天与航海医学]