Influence of Vitamin E on Preventive or Therapeutic Effect of MFA and DTPA in Cadmium Toxicity  

作　　者：S.K.TANDON S.SINGH 

机构地区：[1]IndustrialToxicologyResearchCentre,PostBoxNo.80,MahatmaGnadhiMarg,Lucknow226001,India [2]IndustrialToxic

出　　处：《Biomedical and Environmental Sciences》1995年第1期59-64,共6页生物医学与环境科学（英文版）

摘　　要：The influence of vitamin E supplementation on the ability of α-mercapto-β(2-furyl)acrylic acid (MFA) or calcium trisodium dicthylenetriamine pentaacetate (DTPA) to reduce body burden of cadmium and reverse Cd-induced biochemical alterations was investigated in Cd-exposed rats. The treatment with MFA-vitamin E or CaNa3 DTPAvitandn E was more effective than either vitamin E or chelating agent alone, in depleting blood and tissue Cd. However, the combined treatment showed only limited advantage over the individuals in restoring Cd-induced biochemical changes. Further, the treatment with chelator-vitamin E concomitantly with the exposure to Cd was more effective than post-Cd exposure treatment.

分 类 号：R979.3[医药卫生—药品] R595.2[医药卫生—药学]