苦杏仁药材质量评价法的研究  

Stuides on Evaluation of Semen Armeniacae Amarum

作　　者：胡爽[1] 袁丹[2] 刁桂芬[2] 毕开顺[2] 鹿野美弘[3] 

机构地区：[1]山西医科大学药学院,山西太原030001 [2]沈阳药科大学中成药分析研究室,辽宁沈阳110015 [3]日本北海道药科大学

出　　处：《中国中药杂志》2002年第10期736-739,共4页China Journal of Chinese Materia Medica

摘　　要：目的 :建立苦杏仁药材综合质量评价方法。方法 :用HPLC法测定了苦杏仁药材 14个市售样品、不同年度贮存品及自制炮制品中苦杏仁苷含量 ,并考察了市售药材的常规理化试验项目。结果 :市售药材生品的苦杏仁苷含量与炮制品间差异明显 ,且去皮品中含量均低于药典标准 ,但自制炮制品的含量均达到药典标准 ;不同贮存年度的市售药材生品带皮妥善保存 ,苦杏仁苷含量至少 10年内变化不大 ;市售药材的常规试验项目测定结果表明各种炮制品间的差异较大。结论 :炮制加工过程是影响苦杏仁药材质量的关键因素 ,同时有必要制订其常规理化试验项目 ,加强综合质量控制。Objective: To systematically evaluate the quality of Semen Armeniacae Amarum. Method: The amygdalin content in the samples of Semen Armeniacae Amarum from different markets was analysed by HPLC. Some physical and chemical tests were done to investigate their quality. Result: Some significant differences in amygdalin contents and some physical and chemical parameters were shown between the crude drugs and the processed ones. There are few changes in amygdalin contents with the storage in 17 years. Conclusion: The processing conditions are the main factors that affect the quality of Semen Armeniacae Amarum. Furthermore, a systematic evaluation of the quality of its samples from the different markets has been established by a radar diagram based on the following five parameters: amygdalin contents, the lipid content, ethanol-soluble extract, total ash and acid-insoluble ash.

关 键 词：苦杏仁苷 苦杏仁 质量评价 高效液相色谱法 

分 类 号：R282.71[医药卫生—中药学]