曲马多与芬太尼应用于术后镇痛的观察比较  

Comparision of tramadol and fentanyl in post-operative analgesia

作　　者：祝继洪[1] 章岚[1] 陈洁[1] 

机构地区：[1]浙江大学医学院附属邵逸夫医院,杭州310016

出　　处：《中国航天医药杂志》2002年第5期12-13,共2页Medical Journal of CASE

摘　　要：目的比较曲马多与芬太尼用于术后镇痛的效应和副作用,探讨一种安全有效的术后镇痛方法。方法45例病人分为二组,分别予曲马多1000mg、芬太尼1mg术后静脉持续输注镇痛,采用VAS及Ramsay评分观察镇痛镇静效应及其他副作用。结果曲马多组与芬太尼组相比,镇痛镇静评分、恶心呕吐、尿潴留发生均差异无显著性意义。而曲马多组未出现呼吸抑制,与芬太尼组相比差异有显著性意义。结论曲马多用于术后静脉镇痛效果确切、副作用少。Objective To compare the analgesic effect and s ide effect of tramadol with fentanyl in post -operative in-travenous analgesia .Methods 45patients were randomized to receive 1000mg tramadol(n =23)or 1mg fentanyl(n =22)by continuous intravenous infusion.D egree of pain was measured on visual a nalog scale(VAS).The side effects were evaluated according to the Ramsay scales and th e incidence rate of vomiting,respir ation depression or urinary retenti on.Results The analgesic effect and the incidence r ate of vomiting or urinary retention were similar in both groups ,without significant difference(P>0.05).The incidence rate of respiration d epression in tramadol group was sign ificant less than that of fentanyl group(P<0.05).Conclusion Tramadol is effective and with less s ide effect in post-operative intrav enous analgesia .[

关 键 词：曲马多 芬太尼 术后镇痛 副作用 

分 类 号：R614[医药卫生—麻醉学] R971.2[医药卫生—外科学]