中药制剂临床应用的不良反应原因及对策分析  

Analysis of adverse reactions and countermeasures of clinical application of Chinese medicine preparations

作　　者：张晓霞[1] 

机构地区：[1]河南中医学院第一附属医院,河南郑州450000

出　　处：《中医临床研究》2016年第12期138-139,共2页Clinical Journal Of Chinese Medicine

摘　　要：目的：分析探讨中药制剂临床应用的不良反应（ARDs）原因并据此提出防范对策。方法：回顾性分析2013 年5月—2015 年10 月我院上报的113 例中药制剂的ARDs 报告，整理统计病例的年龄、性别、药品种类及剂量、给药途径、不良反应等。结果：113 例ARDs 报告中女性比例（59.3%）高于男性ARDs（40.7%），0～12 岁小儿（37.2%）及＞60 岁老年人比例（46.9%）是ARDs 的高发对象，给药方式以静脉滴注为主，2013—2015 年ARDs 比例依次为16.8%、34.5%、48.7%，ARDs 临床表现主要在皮肤及附件（46.0%）、消化系统（19.5%）方面。结论：在中药制剂临床应用中ARDs 的发生受多方面因素影响，包括年龄、性别、给药途径等，临床应充分认识到这些影响因素，采取全面有效的ARDs 防范措施，保障中药制剂应用的安全性。Objective: To analyze the causes of adverse medicine reactions (ARDs) in the clinical application of Chinese medicineand to propose the preventive measures. Methods: According to age, gender, drug type and dosage, administration route, adverse reactions,the reports of 113 cases of Traditional Chinese Medicine treatment between 2013.5 to 2015.10 were retrospectively analyzed. Results:Among 113 cases with ARDs, female proportion (59.3%) was higher than that of male (40.7%), higherincidence of ARDs was observedinchildren aged 0～12 (37.2%) and > 60 year old elderly proportion (46.9%) , to give medicine to give priority to the intravenous drip, theproportion of ARDsin 2013,2014 and 2015 being 16.8%, 34.5% and 48.7%.Adverse reactions were mainly observed in skin and itsaccessories (46.0%), and digestive system (19.5%). Conclusion: The occurrence of ARDs during clinical application of Traditional Chinesemedicine is affected by many factors such as age, gender, route of administration, etc. so these factors must be considered carefully to takeeffective measures to prevent ARDs, and to protect the safety of Chinese medicine application.

关 键 词：中药制剂 不良反应 原因 对策 

分 类 号：R288[医药卫生—中药学]