高血压患者亚极量运动时血压变化及其影响因素  

Changes of blood pressure and influence factors in patients with primary hypertension during submaximal exercise

作　　者：汪晓芬[1] 王晓明[1] 张源波[1] 石红玲[1] 和渝斌[1] WANG Xiao-fen;WANG Xiao-ming;ZHANG Yuan-bo;SHI Hong-ling;HE Yu-bin(Department of Cardiology of General Hospital of PLA Beijing Military Area Hospital of Anhui Medical University, Beijing 100700,China)

机构地区：[1]安徽医科大学附属北京军区总医院心内科,北京100700

出　　处：《中国循证心血管医学杂志》2016年第4期503-506,共4页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的 探索原发性高血压患者亚极量运动时血压的变化及其影响因素。方法 连续入选 2014年12月~2015年7月在北京军区总医院就诊的原发性1、2级高血压患者（高血压组）82例和健康体检者（正常组）54例。观察高血压患者亚极量运动时血压变化，并采用多元线性回归分析运动前血压、脉压及踝臂动脉脉搏波传导速度（baPWV）等因素与亚极量运动收缩压的关系。结果 与正常组相比，高血压组亚极量运动收缩压较高[（190±13.2）mmHg vs. （136.7±15.3）mmHg，（1mmHg=0.133kPa）P＜0.05]，上升幅度较高[（39.0±12.1）mmHg vs. （21.7±10.4）mmHg，P＜0.05]。多元线性回归分析显示：运动前收缩压、baPWV及脉压与亚极量运动收缩压线性相关（P＜0.05）。结论 原发性高血压患者亚极量运动时血压升压反应高于正常人，其亚极量运动收缩压与运动前收缩压、baPWV及脉压紧密相关。Objective To explore the changes of blood pressure and its influence factors in primaryhypertension patients during submaximal exercise. Methods 82 patients with primary hypertension ( hypertensiongroup) and 54 normal subjects (normal control group) were enrolled from December 2014 to July 2015. Changes ofblood pressure with primary hypertension during submaximal exercise were measured. Multiple regression analysiswas used to analyze relationship between systolic pressure during submaximal exercise with blood pressure beforeexercise, pulse pressure, and brachial-ankle pulse wave velocity (baPWV). Results Compared with normal controlgroup, systolic pressure during submaximal exercise in hypertension group was higher (190±13.2 mmHg vs. 136.7±15.3 mmHg, P<0.05), with higher rising range (39.0±12.1 mmHg vs. 21.7±10.4 mmHg,P<0.05). Multiplestepwise regression analysis result showed that pre-exercise systolic blood pressure, baPWV and pulse pressurewere related to systolic blood pressure during submaximal exercise (P<0.05). Conclusion In primary hypertensionpatients, blood pressure change during submaximal exercise is higher than normal subjects. Pre-exercise systolicblood pressure, baPWV and pulse pressure were related to systolic blood pressure during submaximal exercise.

关 键 词：原发性高血压 亚极量运动收缩压 踝臂动脉脉搏波传导速度 

分 类 号：R544.1[医药卫生—心血管疾病]