不同程度冠状动脉病变患者介入治疗前后生活质量变化  

Quality of life of patients with different degrees of coronary artery disease before and after percutaneous coronary intervention

作　　者：张安宁[1] 张海涛[1] 孙津津[1] 黄丛春[1] 罗惠兰[1] ZHANG An-ning;ZHANG Hai-tao;SUN Jin-jin;HUANG Cong-chun;LUO Hui-lan(Clinical College of Chinese PLA Air Force, Anhui Medical University, Hefei 230032, China)

机构地区：[1]安徽医科大学空军临床学院,合肥230032

出　　处：《中国循证心血管医学杂志》2016年第6期720-724,共5页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的 初步探讨不同程度冠状动脉病变患者介入治疗前后生活质量的变化及差异。 方法前瞻性纳入空军总医院2013年5月~2014年5月期间行冠状动脉支架置入且术后服药依从性良好的150例冠心病患者，根据Gensini评分分为轻、中、重度三组，采用一般临床资料调查表、西雅图心绞痛生存质量量表（SAQ）分别对患者治疗前24 h、治疗后12月进行问卷调查，并及时准确收集问卷调查结果。分析比较三组患者术前、术后12月的生活质量的变化及差异。结果 一般临床资料对比：轻度与重度病变组在冠心病类型、支架置入数目上差异有统计学意义（P＜0.017）；中度与重度病变组在支架置入数目上差异有统计学意义（P＜0.017）；轻中重度三组在病变血管数目上两两比较差异均有统计学意义（P＜0.017）。轻、中、重三组患者术后较术前生活质量均有显著改善，差异具有统计学意义（P＜0.05）。冠状动脉介入术前，轻度与重度病变组在躯体活动受限程度、治疗满意程度上有差异（P＜0.017）；中度和重度病变组在躯体活动受限程度上有差异（P＜0.017），冠状动脉介入术后，三组之间生活质量对比未见明显差异（P＞0.05）。结论 不同程度冠状动脉病变患者介入治疗术后生活质量均较术前显著改善。在介入治疗前生活质量的差异主要表现在躯体活动受限程度及治疗满意程度方面，术后生活质量未见明显差异。Objective To evaluate quality of life of patients with different degrees of coronary artery diseasebefore and after percutaneous coronary intervention (PCI). Method From May 2013 to May 2014, coronary heartdisease (CHD) patients (n=150) undergone coronary angiography (CAG) and stenting were chosen. The patientswere divided into three Groups (mild lesion group, moderate lesion group and sever lesion group) according totheir Gensini scores, and all patients were interviewed by Seattle Angina Questionnaire (SAQ) and general clinicalquestionnaire 24 hours before and 12 months after PCI, respectively. Difference of quality of life (QOL) among threegroups were observed respectively 24 h before and 12 m after PCI. Result Comparison of general clinical data:types of coronary artery disease and the number of stent implantation were different between mild lesion group andsever lesion group (P<0.017); the number of stent implantation was different between moderate lesion group andsever lesion group (P<0.017); the number of lesion blood vessel was different among three groups (P<0.017). TheQOL was improved in three groups after PCI (P<0.05). Before PCI, the level of physical limitation and treatmentsatisfaction were different between mild lesion group and sever lesion group (P<0.017); and the level of physicallimitation was different between moderate lesion group and sever lesion group (P<0.017). The QOL were notsignificantly different in three groups 12 m after PCI (P>0.05). Conclusion PCI can improve the quality of life ofpatients with different severity of coronary artery disease .Different severity of coronary artery disease influence thephysical limitation ,treatment satisfaction in pre-operation and there was no significant difference quality of life inthree groups after PCI.

关 键 词：冠心病 GENSINI评分 经皮冠状动脉介入治疗(PCI) 西雅图心绞痛生活质量量表(SAQ) 生活质量 

分 类 号：R541.4[医药卫生—心血管疾病]