207例慢性乙肝患者幽门螺旋杆菌感染率观察  

作　　者：张春华[1] 

机构地区：[1]吉林医药学院附属医院消化内科,吉林132013

出　　处：《当代医学》2016年第22期38-39,共2页Contemporary Medicine

摘　　要：目的观察和分析慢性乙肝患者幽门螺旋杆菌的感染率等情况,为临床治疗工作提供参考。方法选择入院治疗和体检的207例乙肝患者和50名健康人群作为本次调查研究的对象,比较全体对象的Hp-Ig G阳性率,乙肝患者的HBV-DNA与Hp-Ig G阳性率关系等情况。结果在全体对象的Hp-Ig G阳性率比较方面,在207例乙肝患者中,71.50%呈阳性;在50名健康人群中,24.00%呈阳性;2组比较差异有统计学意义(P<0.05)。重点针对乙肝患者的幽门螺旋杆菌感染情况进行分析,如HBV-DNA检测方面,HBV-DNA<103的乙肝患者,Hp-Ig G阳性率为50.98%;而HBV-DNA>103的乙肝患者,Hp-Ig G阳性率为78.21%;2组比较差异有统计学意义(P<0.05)。结论慢性乙肝患者幽门螺旋杆菌感染的发生率明显高于健康人群,且HBV-DNA含量、肝功能检测结果和并发症发生率均与幽门螺旋杆菌的感染率存在对应关系。Objective To observe and analyze the infection rate of helicobacter pylori in patients with chronic hepatitis B, to provide reference for clinical treatment. Methods 207 cases of hepatitis B patients and 50 healthy people were selected as the research object, the Hp-IgG positive rate of hepatitis B and Hp-IgG positive rate were compared. Results The positive rate of Hp-IgG was 71.50% in 207 patients. In 50 healthy people, 24% was positive. The difference between the two groups was statistically significant (P<0.05); the emphasis was on the analysis of Helicobacter pylori infection in patients with hepatitis B, such as HBV-DNA, HBV-DNA<103, Hp-IgG positive rate was 50.98%. In the HBV-DNA>103 of hepatitis B patients, the positive rate of Hp-IgG was 78.21%. The difference between the two groups was statistically significant (P<0.05). Conclusion The incidence of Helicobacter pylori infection in chronic hepatitis B patients was significantly higher than that of healthy people, and the HBV-DNA content, liver function test results and complication incidence were related to the infection rate of helicobacter pylori.

关 键 词：慢性乙型肝炎 幽门螺旋杆菌 

分 类 号：R512.62[医药卫生—内科学]