多发性骨髓瘤的免疫基因治疗  

The Research Progress of Immune Gene Therapy on the Treatment of Multiple myeloma

作　　者：秋玉珍 张铀[1] QIU Yu-zhen;ZHANG You(Dept.of Hematology,The 2st Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650101,China)

机构地区：[1]昆明医科大学第二附属医院血液科,云南昆明650101

出　　处：《昆明医科大学学报》2016年第6期1-4,共4页Journal of Kunming Medical University

基　　金：国家自然科学基金资助项目(81160074)

摘　　要：多发性骨髓瘤(multiple myeloma,MM)是一种恶性浆细胞单克隆增生性疾病,约占全部恶性肿瘤的1%,目前仍不能治愈,微小残留病是主要原因,因此,清除微小残留病,有可能治愈本病.在各种治疗方法中,针对多发性骨髓瘤的免疫基因疗法(Immune gene therapy或Immunogene therapy)是当今治疗的研究热点,近几年免疫基因疗法在体内外实验中取得了较好的结果,本文就免疫基因在多发性骨髓瘤治疗中的研究及应用进行综述.Multiple myeloma (MM) is a malignant plasma cell disease, accounting for about 1% of all malignant tumors, is still uncurable, minimal residual disease(MRD) is the reason, therefore,removal of minimal residual disease maybe possible to cure the disease. In a variety of treatment methods, immune gene therapy for multiple myeloma is a hot research topic in recent years, has achieved good results in vitro and in vivo experiments,in this review immune genes therapy in multiple myeloma research would be discussed.

关 键 词：多发性骨髓瘤 免疫疗法 基因疗法 

分 类 号：R503[医药卫生—内科学]