植骨术配合独活寄生汤治疗胫骨下段骨折延迟愈合时血液流变学指标的变化  

The Clinical Effect of Ilium Grafting Combined with Duhuojishengtang on Patients with Delayed Fracture Healing and the Changes of Hemorheology of Patients

作　　者：贺小龙 朱东[2] HE Xiao-long;ZHU Dong(Dept. of Surgery,People’s Hospital of Qingjian County,Yulin City,Yulin Shaanxi 718300;Dept. of Orthopedics,The No.1 Hospital of Jilin University,Changchun Jilin 130031,China)

机构地区：[1]榆林市清涧县人民医院外科,陕西榆林718300 [2]吉林大学第一附属医院创伤骨科,吉林长春130031

出　　处：《昆明医科大学学报》2016年第6期61-64,共4页Journal of Kunming Medical University

基　　金：国家自然科学基金资助项目(11272134)

摘　　要：目的探讨植骨术配合独活寄生汤治疗胫骨下段骨折延迟愈合的临床疗效及对患者血液流变学指标的影响.方法将收治的80例胫骨下段骨折延迟愈合患者随机分为观察组和对照组,其中对照组40例,行髂骨移植术进行治疗;观察组40例在行髂骨移植术基础上加服独活寄生汤进行治疗.观察2组患者的临床疗效,并记录术后及治疗各阶段患者血液流变学指标变化.结果观察组的痊愈率为62.5%,治疗总有效率为92.5%,显著高于对照组痊愈率35.0%和总有效率72.5%,差异有统计学意义(P<0.01);植骨术后,2组患者各血液流变学指标比较,差异无统计学意义(P>0.05),而在完成第1疗程、第2疗程及第3疗程后,观察组患者各血液流变学指标均优于对照组,差异有统计学意义(P<0.05).结论植骨术配合独活寄生汤可改善胫骨下段骨折延迟愈合患者血液流变学,提高患者痊愈率和有效率,安全性高,值得临床广泛推广.Objective To investigate the clinical effect of ilium grafting combined with Duhuojishengtang on the delay fracture healing and explore the effect on hemorheology. Methods Eighty patients with delayed fracture healing were randomly divided into two groups. Forty patients in control group were treated by ilium grafting and 40 patients in observation group were treated by ilium grafting combined with Duhuojishengtang. The clinical effect was observed after treatment and indexes of hemorheology were recorded after different treatment time. Results The cure rate of observation group was 62.5%,which was significantly higher than that of control group 35.0%, the effective rate of observation group was 92.5%, which was significantly higher than that of control group 72.5% ( P<0.01) .There were no significant differences between two groups in indexes of hemorheology after ilium grafting ( P>0.05) . After the first, second, third course, the indexes of hemorheology of observation group were better than those of control group, with statistically significant differences ( P<0.05) . Conclusions Ilium grafting combined with duhuojishengtang can improve the indexes of hemorheology, improve the cure and effective rate and also has high security. It has high clinical value and worth of popularization and application.

关 键 词：胫骨下段骨折 骨折延迟愈合 髂骨植骨术 独活寄生汤 

分 类 号：R683.42[医药卫生—骨科学]