某综合性教学医院ICU鲍曼不动杆菌分布情况及耐药分析  

Analysis of distribution and drug resistance of Acinetobacter baumnnii in ICU of a comprehensive teaching hospital

作　　者：郜莉娜[1] 孟灵[1] 朱金芬[1] 李菲菲[1] 冯芳[2] Gao Lina;Meng Ling;Zhu Jinfen;Li Feifei;FengFang(Laboratory Medcine Center, LanZhou University Second Hospital,LanZhou 730030,China;Surgical ICU, LanZhou University Second Hospital,LanZhou 730030,China)

机构地区：[1]兰州大学第二医院检验医学中心,甘肃兰州730030 [2]兰州大学第二医院外科ICU,甘肃兰州730030

出　　处：《甘肃医药》2016年第8期566-568,共3页Gansu Medical Journal

基　　金：甘肃省自然科学基金项目(编号:1107RJZA211;1506RJZA230)

摘　　要：目的：分析我院ICU病房分离的鲍曼不动杆菌的来源分布及耐药情况，为医院感染的防控提供依据。方法：对2013~2015年我院ICU病房各类标本中分离的鲍曼不动杆菌进行分布及耐药率的统计分析。结果：我院ICU病房鲍曼不动杆菌主要来源为痰(77%~79.4%)，其次为血液(4.5%~7.5%)、导管(1.2%~6.2%)、伤口分泌物(2.8%~4.7%)等；多重耐药鲍曼不动杆菌检出率高(78.08%~79.43%)；对头孢菌素类、氨基糖苷类、亚胺培南的耐药率均高达86%~90%，对左氧氟沙星的耐药率为45.7%~64.8%，对米诺环素的耐药率为17.8%~46.4%，对头孢哌酮/舒巴坦的耐药率为6.6%~13.5%。结论：我院ICU病房分离出鲍曼不动杆菌耐药率高，多重耐药鲍曼不动杆菌比例高。Objective: To investigate the distribution and antibiotic resistance of acinetobacter baumannii in ICU patients, whichwould provide a basis for rational use of antibiotics. Methods:The distribution and antibiotic resistance of Acinetobacter baumannii isolatedfrom ICU patients were analyzed from 2013 to 2015. Results:The main source of acinetobacter baumannii isolated from the ICU patients wassputum (77%-79.4%), followed by blood (4.5%-7.5%)、catheter (1.2%-6.2%)、wound secretion (2.8%-4.7%).The resistance rate of acineto?bacter baumannii to cephalosporins, aminoglycosides, imipenem was up to 86%-90%,and the resistance rate to levofloxacin was 45.7%-64.8%, minocycline was 17.8%-46.4%, and cefoperazone/sulbactam was 6.6%-13.5%, respectively. Conclusions:There exists a high level of antibiotic resistance of the acinetobacter baumnnii in ICU patients. Meanwhile the rate of multidrug-resistant is also a higher level in acinetobacter baumannii.

关 键 词：鲍曼不动杆菌 分布 耐药率 

分 类 号：R37[医药卫生—病原生物学]