痰培养联合尿抗原检测肺炎链球菌在婴幼儿细菌性肺炎诊治中的应用  

Application of sputum culture combined with urinary antigen detection for streptococcus pneumonia in infants and young children

作　　者：荆彩霞 Jing Caixia(Clinical Laboratory,the Second People's Hospital of Pingliang City,Gansu Province 744000)

机构地区：[1]甘肃省平凉市第二人民医院检验科,744000

出　　处：《中国社区医师》2016年第22期144-145,共2页Chinese Community Doctors

摘　　要：目的:探讨痰培养联合尿肺炎链球菌抗原检测对婴幼儿细菌性肺炎感染的临床价值。方法:收治下呼吸道感染患儿213例,行痰液细菌分离培养和鉴定药敏,同时采用免疫层析法检测尿肺炎链球菌多糖抗原。结果:痰液培养阳性率11.2%,尿肺炎链球菌抗原阳性率23.0%,痰液培养阳性组的尿肺炎链球菌抗原阳性率100%,明显高于阴性组的18.2%(P<0.01)。尿肺炎链球菌抗原检测敏感性100%,特异性81.8%,准确度84.0%。结论:尿抗原检测肺炎链球菌技术在婴幼儿肺炎链球菌感染引起的肺炎的诊断中有确切价值,与痰培养联合可以提高诊断符合率,为患儿的诊断治疗提供细菌学参考依据和抗生素选择依据。Objective:To explore the application of sputum culture combined with urinary antigen detection for streptococcuspneumonia in infants and young children.Methods:213 cases of children with lower respiratory tract infection were selected.Theywere given sputum bacteria culture and identification and drug sensitivity,at the same time,we detected urinary pneumococcalpolysaccharide antigen by immune chromatography.Results:The positive rate of sputum culture was 11.2% ;the positive rate ofurinary pneumococcal antigen was 23%;the positive rate of urinary pneumococcal antigen in children with positive sputum culturewas 100% ,which was significantly higher than 18.2% of the negative group(P<0.01).The sensitivity of urinary streptococcuspneumoniae antigen detection was 100% ;specificity was 81.8% ;accuracy was 84% .Conclusion:Urinary antigen detection ofstreptococcus pneumoniae technology had the exact value in the diagnosis of infant pneumonia caused by streptococcuspneumoniae,combined with sputum culture can improve the diagnostic accordance rate,and it can provide bacteriologicalreference and antibiotic selection basis for diagnosis and treatment of children.

关 键 词：细菌性肺炎 肺炎链球菌 尿肺炎链球菌抗原检测 婴幼儿 耐药性 

分 类 号：R725.6[医药卫生—儿科]