不规律服用降压药对原发性高血压患者治疗效果的影响  

Effect of irregular antihypertensive drugs on patients with essential hypertension

作　　者：杨超[1] 孟小姣 沈先月 房剑[1] Yang Chao;Meng Xiaojiao;Shen Xianyue;Fang Jian(Department of Preclinical Medicine,the Medical College in Anhui University of Science and Technology 232001)

机构地区：[1]安徽理工大学医学院基础医学系,232001

出　　处：《中国社区医师》2016年第13期33-34,共2页Chinese Community Doctors

基　　金：国家级大学生创新创业训练计划项目(AH201310361198)~~

摘　　要：目的:探讨不规律服用降压药物对原发性高血压病患者降压效果的影响。方法:回顾性分析原发性高血压病患者的临床资料,比较规律服药组和不规律服药组的治疗效果。结果:两组微量尿白蛋白、血肌酐、左心室后壁厚度、C-反应蛋白比较,差异有统计学意义(P<0.05)。两组治疗后SBP、DBP、MAP均明显下降,差异有统计学意义(P<0.01)。治疗后规律服药组的血压下降程度优于不规律服药组,差异有统计学意义(P<0.01)。治疗后不规律服药组CV明显高于规律服药组(P<0.01)。结论:不规律服药患者的靶器官损伤较规律服药患者加重。Objective:To investigate the antihypertensive effect of irregular antihypertensive drugs on patients with essentialhypertension.Methods:The clinical data of patients with essential hypertension were analyzed retrospectively,and the clinicaleffect of the regular medication group and the irregular medication group were compared.Results:There were statisticallysignificant differences of microalbuminuria,serum creatinine,left ventricular posterior wall thickness and C-reaction proteinbetween groups(P<0.05).The SBP,DBP,MAP of the two groups after treatment were significantly decreased,and the differenceswere statistically significant(P<0.01).The blood pressure of the regular medication group decreased more than that of theirregular medication group,and the difference was statistically significant(P<0.01).After the treatment,the CV of the irregularmedication group was significantly higher than that of the regular medication group(P<0.01).Conclusion:The target organ damageof patients with irregular medication were more serious than that of the patients with regular medication.

关 键 词：原发性高血压 不规律服药 变异系数 靶器官损伤 

分 类 号：R544.11[医药卫生—心血管疾病]