复方甘草酸苷片与他克莫司软膏在湿疹和特应性皮炎治疗中的应用  

Application of Compound Glycyrrhizin Tablets and Tacrolimus Ointment in Treatment of Eczema and Atopic Dermatitis

作　　者：沈跃莉[1] Shen Yue-li(Dermatology & STD Department,The First Affiliated Hospital of Chengdu Medical College,Chengdu 610500, China)

机构地区：[1]成都医学院第一附属医院皮肤性病科,成都610500

出　　处：《中国医药导刊》2016年第8期826-827,829,共3页Chinese Journal of Medicinal Guide

摘　　要：目的：分析复方甘草酸苷片与他克莫司软膏在湿疹和特应性皮炎治疗中的应用效果，为临床工作提供有价值参考。方法：收集分析2015年5月～2016年5月我院收治的湿疹和特应性皮炎患者50例作为研究对象，随机分为实验组和对照组，对照组采用糠酸莫米松乳膏治疗，实验组使用复方甘草酸苷片联合他克莫司软膏，比较两组临床效果。结果：实验组治疗总有效率92.0%，明显高于对照组68.0%，对照组不良反应总发生率44.0%，明显高于实验组20.0%，差异显著，具有统计学意义（P＜0.05）。结论：在湿疹和特应性皮炎的治疗中使用复方甘草酸苷片和他克莫司软膏，具有良好的临床效果，疗效确切、安全可靠，不良反应少。Objective: To analyze the application effect of Compound Glycyrrhizin Tablets and Tacrolimus Ointment in the treatment of eczema and atopic dermatitis,and to provide valuable reference for clinical work.Methods:To collect and analyze may 2015 - 2016 years 5 months in our hospital from eczema and atopic dermatitis patients 50 cases as the object of study,were randomly divided into experimental group and control group,the control group was treated with mometasone furoate cream in the treatment,experimental group use compound glycyrrhizin tablets joint tacrolimus ointment,compared two groups of clinical effect.Results:The total effective rate of the experimental group was 92% higher than that of the control group 68%,the incidence of adverse reactions in the control group was 44% higher than that of the experimental group 20%,the difference was statistically significant(P<0.05).Conclusion:In the eczema and atopic dermatitis treatment using compound glycyrrhizic acid glucoside tablets and tacrolimus ointment has good clinical effect,curative effect is exact,safe and reliable,less adverse reaction.

关 键 词：复方甘草酸苷片与他克莫司软膏 湿疹和特应性皮炎 应用效果 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]