流式细胞学检测三阴性乳腺癌的生物学意义  

The biological significance of flow cytometry on three negative breast cancer

作　　者：张景臣[1] 刘薇[1] 毛大华[2] Zhang Jingchen;Liu Wei;Mao Dahua(Department of Galactophore,Zhengzhou People's Hospital,450000;The First Affiliated Hospital of Guiyang Medical University,550000)

机构地区：[1]郑州人民医院乳腺科,450000 [2]贵阳医学院第一附属医院,550000

出　　处：《中国社区医师》2016年第28期9-10,共2页Chinese Community Doctors

摘　　要：目的:探讨S期细胞比率、倍体表达在三阴性乳腺癌与非三阴性乳腺癌之间的差别。方法:通过流式细胞仪检测135例乳腺SPF及倍体表达情况。结果:19例三阴性乳腺癌中SPF(9.32±4.89);116例非三阴性乳腺癌SPF(5.65±4.14),差异具有统计学意义。结论:高表达的SPF与年龄、临床分期有明显相关性,而与淋巴结有无转移、肿块大小无明显相关性。Objective:To investigate the difference of cell ratio in the S stage and ploidy expression between three negative breastcancer and non three negative breast cancer.Methods:The expression of SPF and ploidy in 135 cases were detected by flowcytometry.Results:The expression of SPF in 19 cases of three negative breast cancer was(9.32±4.89);while in 116 cases of nonthree negative breast cancer was(5.65±4.14),the difference was statistically significant.Conclusion:High expression of SPF has asignificant correlation with age and clinical stage,however,it has no correlation with lymph node metastasis and tumor size.

关 键 词：三阴性乳腺癌 流式细胞学检测 S期细胞比率 倍体表达 

分 类 号：R737.9[医药卫生—肿瘤]