睡眠呼吸暂停与子痫前期相关性研究  

Correlation research between sleep apnea and preeclampsia

作　　者：彭久君[1] 袁佩[1] Peng Jiujun;Yuan Pei(The Maternal and Child Health Hospital of Changzhou City Affiliated to Nanjing Medical University 213000)

机构地区：[1]南京医科大学附属常州市妇幼保健院,213000

出　　处：《中国社区医师》2016年第30期106-106,108,共2页Chinese Community Doctors

基　　金：常州市科技局项目(CJ20112003)~~

摘　　要：目的:探讨睡眠呼吸暂停和子痫前期的相关性。方法:收治子痫前期合并SAHS孕妇25例作为观察1组,子痫前期无SAHS孕妇40例作为观察2组,选取25例正常孕妇作为对照组。比较3组呼吸暂停低通气指数、最低血氧饱和度、IL-6和TNF-α。结果:对照组AHI和LSaO_2与观察2组比较,差异无统计学意义(P>0.05)。对照组AHI和LSaO_2与观察1组比较,差异具有统计学意义(P<0.05)。对照组TNF-α、IL-6与观察2组比较,差异具有统计学意义(P<0.01)。观察1组TNF-α、IL-6与对照组比较,差异具有统计学意义(P<0.01)。结论:睡眠呼吸暂停是子痫前期疾病发生的危险因素。Objective:To investigate the correlation between sleep apnea and preeclampsia.Methods:25 cases of pregnant womenwith preeclampsia combined with SAHS were as the observation group 1;40 cases of pregnant women with preeclampsia withoutSAHS were as the observation group 2;25 cases of normal pregnant women were as the control group.The apnea hypopnea index,lowest oxygen saturation,IL-6 and TNF-α in the three groups were compared.Results:There was no statistically significantdifference of AHI and LSaO2 between the control group and the observation group 2 (P>0.05).There were statistically significantdifferences of AHI and LSaO2 between the control group and the observation group 1 (P>0.05).There were statistically significantdifferences of IL-6,TNF-αbetween the control group and the observation group 2 (P<0.01).There were statistically significantdifferences of IL-6,TNF-α between the control group and the observation group 1 (P<0.01).Conclusion:Sleep apnea was riskfactor for the occurrence of preeclampsia.

关 键 词：睡眠呼吸暂停 子痫前期 相关性 

分 类 号：R714.244[医药卫生—妇产科学]