VEGF和PEDF对血管渗透性影响的研究进展  

Research progress on the effect of VEGF and PEDF on vascular permeability

作　　者：赵静[1] 闫伟[2] 雷平[1] Zhao Jing;Lei Ping(Corresponding author);Yan Wei(Tianjin Medical University General Hospital 300052;Tianjin City Children's Hospital 300074)

机构地区：[1]天津医科大学总医院,300052 [2]天津市儿童医院,300074

出　　处：《中国社区医师》2016年第31期7-7,9,共2页Chinese Community Doctors

摘　　要：目的:血管渗透性是维系血管功能的重要方面,而血管渗透性主要受血管内皮细胞间连接和周细胞功能状态等影响。血管内皮生长因子(VEGF)和色素上皮细胞源因子(PEDF)对血管渗透性的影响就与这些因素密切相关,并且两者也有直接或间接的联系。本文将就VEGF和PEDF与血管渗透性的关系为中心点,以血管渗透性的角度对VEGF和PEDF有一个较全面的认识。Vascular permeability is an important aspect of maintaining vascular function,and vascular permeability is mainly affected by the connection between vascular endothelial cells and the function of peripheral blood vessels.The effects of vascular endothelial growth factor(VEGF) and pigment epithelium derived factor(PEDF) on vascular permeability are closely related to these factors,and they also have direct or indirect contact.This article will be on the relationship between VEGF and PEDF and vascular permeability as the center point,which has a more comprehensive understanding of VEGF and PEDF in terms of vascular permeability.

关 键 词：VEGF PEDF 血管渗透性 细胞连接 

分 类 号：R54[医药卫生—心血管疾病]