奥司他韦治疗儿童流行性感冒样病例的临床观察  

Clinical observation of oseltamivir in the treatment of influenza- like illness for children

作　　者：刘龙魂 林立 刘德强 曾贵华 LIU Long -hun;LIN Li;LIU De -qiang;ZENG Gui hua(Department of Pediatrics ^Tangxia hospital of Do?igguan, Guangdong ,Dongguan 523721, China)

机构地区：[1]广东省东莞市塘厦医院儿科，广东 东莞 523721

出　　处：《吉林医学》2016年第7期1631-1632,共2页Jilin Medical Journal

摘　　要：目的:探讨奥司他韦在儿童流行性感冒(流感)样病例中的临床治疗效果。方法:选取300例儿童流感样病例,随机分为两组,每组150例。对照组采用利巴韦林颗粒治疗,试验组采用奥司他韦颗粒治疗,比较两组临床疗效。结果:试验组治疗总有效率为92.67%,显著高于对照组的76.67%,差异有统计学意义(P<0.05);试验组体温恢复正常时间、咳嗽、咽痛、鼻塞、流涕缓解时间,显著短于对照组,差异有统计学意义(P<0.05);实验组药物不良反应发生率为6.00%,显著低于对照组的14.00%,差异有统计学意义(P<0.05)。结论:儿童流感样病例采用奥司他韦治疗效果理想,能提高临床治疗效果,改善患儿症状,值得推广应用。Objective To investigate the clinical oseltamivir treatment of influenza - like illness in children. Method 300 casesof children influenza - like illness were selected and randomly divided into two groups, 150 cases in each group. The controlgroup with ribavirin particle therapy,the experimental group oseltamivir particle therapy,the clinical efficacy of two groups was compared.Results The total effective rate of experimental group was 92. 6 7 % , significantly higher than the control group 76. 6 7 % ,thedifference was statistically significant ( P < 0. 05 ) ; the experimental group returned to normal body temperature, cough, sore throat /nasal congestion / runny remission time was significantly shorter than the control group, the difference was statistically significant(P <0.05); the experimental group, adverse drug reactions was 6. 0 % , significantly lower than the control group 14. 0 0 % , thedifference was statistically significant ( P < 0. 05 ). Conclusion Children influenza - like illness treatment using oseltamivir desiredeffect,can improve clinical outcomes,improve symptoms in children,should be widely applied.

关 键 词：奥司他韦 利巴韦林 儿童 流行性感冒 

分 类 号：R725.1[医药卫生—儿科]