大脑白质纤维束与算术能力的关系  

Atlas-based Analysis of Association Between Cerebral White Matter Fiber Tracts and Arithmetic Ability

作　　者：李淮周 钟宁[1,2,3,4] 杨阳[2,3,4] 周海燕[1,2,3] 杨孝敬[1,2,3] 郭家梁[1,2,3] 马小萌[1,2,3] LI Huaizhou;ZHONG Ning;YANG Yang;ZHOU Haiyan;YANG Xiaojing;GUO Jialiang;MA Xiaomeng(International W I C Institute,Beijing University of Technology,Beijing 100124,China;Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics,Beijing 100124,China;Beijing International Collaboration Base on Brain Informatics and Wis d o m Services,Beijing 100124,China;Department of Life Science and Informatics,Maebashi Institute of Technology,Maebashi 371-0816,Japan)

机构地区：[1]北京工业大学国际WIC研究院,北京100124 [2]磁共振成像脑信息学北京市重点实验室,北京100124 [3]脑信息智慧服务北京市国际科技合作基地,北京100124 [4]前桥工业大学生命科学与信息工程系

出　　处：《北京工业大学学报》2016年第10期1565-1571,共7页Journal of Beijing University of Technology

基　　金：国家重点基础研究发展计划资助(2014CB744600);北京市自然科学基金资助项目(4164080)

摘　　要：为了探索大脑白质纤维束与算术运算能力的关系,设计了一个认知功能实验测试所有受试者的算术能力,然后采集T1结构像和弥散张量成像.使用约翰霍普金斯大学白质纤维束图谱提取每条纤维束的平均各向异性分数(fractional anisotropy,FA),并与行为数据进行相关性分析.结果显示:减法得分与右扣带束(扣带回区域)和右下纵束的FA值呈正相关,算术运算的反应时均与右上纵束(颞叶部分)的FA值呈负相关,并且这些相关与任务的困难差异无关.结果表明:大脑白质纤维束连贯性或髓鞘化的增强可能会提高某些算术能力,进一步为算术运算的神经基础提供了新的证据.To investigate the association between cerebral white-matter fiber tracts and arithmetic ability,an experiment of cognitive function was designed to test arithmetic ability of all subjects. Then, T1 structural image and diffusion tensor imaging were collected. The average fractional anisotropy ( F A ) value of each fiber bundle was extracted by the white matter tractography atlas of Johns Hopkins University. The correlation between FA values of fiber tracts and behavior data was performed. Results show that the subtraction scores have a positive correlation with the FA values in the right cingulum ( cingulate gyrus ) and the right inferior longitudinal fasciculus. The FA values of the right superior longitudinal fasciculus ( temporal part) are negatively correlated with the reaction times of arithmetic operations, respectively. These observed significant correlations are not just an effect of task difficulty.The increasing fiber coherence or myelination contribute to the improvement of arithmetic ability. This study further provides new evidences for the neural basis of sarithmetic operations.

关 键 词：弥散张量成像 白质纤维束 各向异性分数 算术运算 

分 类 号：R445.2[医药卫生—影像医学与核医学]