苯甲酰甲酸参与的脱羧偶联反应研究进展  

Research progress on decarboxylative cross-coupling of α-oxocarboxylic acids

作　　者：褚金鹏 王炳福[1] 王翠苹[1] 张志强[1] CHU Jinpeng;WANG Bingfu;WANG Cuiping;ZHANG Zhiqiang(School of Chemical Engineering,Key Laboratory for Functional Material,Educational Department of Liaoning Province,University of Science and Technology Liaoning,Anshan 114051,China)

机构地区：[1]辽宁科技大学化学工程学院辽宁省功能材料重点实验室,辽宁鞍山114051

出　　处：《辽宁科技大学学报》2016年第5期370-375,共6页Journal of University of Science and Technology Liaoning

基　　金：国家自然科学基金(21542017);辽宁科技大学优秀人才培养项目(2015RC08)

摘　　要：过渡金属催化的脱羧偶联反应已成为构建C-C键的首选方法。苯甲酰甲酸作为一种活泼的脱羧试剂,可实现吡嗪、芳卤、吡啶、芳基羧(硼)酸、酰胺、肟醚和吲哚的脱羧偶联反应,进而制备对应的芳基甲酮类化合物。本文根据不同的底物对近年来苯甲酰甲酸参与的脱羧偶联反应进行综述。Transition- metal- catalyzed decarboxylative cross-coupling has emerged as a powerful tool for theconstruction of C-C bonds. The decarboxylative cross-couplings of aromatic heterocycles,aryl halides,potassiumaryltrifluoroborates,benzoic acids,acetanilides and o-methyl oximes have been achieved using α-oxocarboxylicacids as the acylating agents leading to the aryl ketones. The recent progress was reviewed accordingto the different types of substrates.

关 键 词：苯甲酰甲酸 脱羧反应 C-C偶联 酰基化反应 

分 类 号：O626.1[理学—有机化学]