奥拉西坦联合尼莫地平治疗重症脑挫裂伤的临床观察  

The clinical observation of oxiracetam combined with nimodipine in the treatment of severe cerebral contusion

作　　者：张林[1] Zhang Lin(Chongqing Public Health and Medical Treatment Center 400021)

机构地区：[1]重庆市公共卫生医疗救治中心,400021

出　　处：《中国社区医师》2017年第3期25-26,共2页Chinese Community Doctors

摘　　要：目的:研究、分析应用奥拉西坦联合尼莫地平治疗重症脑挫裂伤的临床效果。方法:收治重症脑挫裂伤患者60例,随机分成两组,每组30例。对照组进行缓慢静脉滴注生理盐水+尼莫地平液体。观察组在此基础之上联合使用奥拉西坦。2周后对两组患者的治疗情况及神经功能缺损(NIHSS)评分变化情况进行比较。结果:治疗后,对照组的总有效率73.3%,低于观察组的90.0%,两组差异有统计学意义(P<0.05);治疗前两组NIHSS评分高于治疗后(P<0.05),且对照组治疗后的NIHSS评分明显高于观察组(P<0.05)。结论:应用奥拉西坦联合尼莫地平治疗脑挫裂伤效果好,患者的NIHSS评分显著改善。Objective:To study and analyze the clinical application effect of oxiracetam combined with nimodipine in the treatment of severe cerebral contusion.Methods:60 cases of severe cerebral contusion were selected.They were randomly divided into the two groups,with 30 cases in each.Patients in the control group were treated with slow intravenous infusion of saline combined with nimodipine liquid,while the observation group was treated with oxiracetam on the basis of the control group.Two weeks later,the treatment and neurologic deficits(NIHSS)scores were compared between groups.Results:After treatment,the totaleffective rate of the control group was 73.3% ,lower than 90.0% of the observation group,the difference between groups wasstatistically significant(P<0.05).Before treatment,the NIHSS scores of the two groups were higher than those after treatment(P<0.05),and the NIHSS scores of the control group after treatment were significantly higher than that of the observation group(P<0.05).Conclusion:Oxiracetam combined with nimodipine in the treatment of cerebral contusion has good curative effect,and the NIHSS scores are significantly improved.

关 键 词：奥拉西坦联合尼莫地平 尼莫地平 重症脑挫裂伤 

分 类 号：R651.15[医药卫生—外科学]