186例艾滋病痴呆复合征中医证型分布特点  

TCM Syndrom Type Distribution Characteristics for 186 Cases of AIDS Dementia Complex

作　　者：张雪[1] 蒋自强[2] 陈丽华[2] 孙燕[1] 杨萱[1] 王双利[1] 安永辉[1] 张晓华[1] 焦敏[1] 张静[1] ZHANG Xue;JIANG Zi-qiang;CHEN Li-hua;SUN Yan;YANG Xuan;WANG Shuang-li;AN Yong-hui;ZHANG Xiao-hua;JIAO Min;ZHANG Jing(The Sixth People’s Hospital of Zhengzhou, Zhengzhou 450000,China;Institute of AIDS, The First Affiliated Hospital of Henan University of TCM, Zhengzhou 450000, China)

机构地区：[1]郑州市第六人民医院,河南郑州450000 [2]河南中医学院第一附属医院艾滋病临床研究中心,河南郑州450000

出　　处：《中国中医药信息杂志》2017年第3期14-17,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：河南省中医药科学研究专项课题(2014ZY02087)

摘　　要：目的研究艾滋病痴呆复合征(ADC)各证型与不同病情程度、年龄、CD4+T细胞计数及感染途径的关系。方法对186例ADC患者进行辨证,分析各证型在不同病情程度、不同年龄、不同CD4+T细胞计数及不同感染途径中的分布情况。结果肾虚髓减证、肝肾阴虚证、心脾两虚证、痰浊阻窍证、气虚血瘀证分别为48、51、15、37、35例。病情程度以中、重度居多,肝肾阴虚证多见;不同病情程度中各证型分布比较,差异有统计学意义(χ~2=82.495,P=0.000)。不同年龄段中以肾虚髓减证、肝肾阴虚证多见,患者多分布于>50~60岁和>60岁2个年龄段;不同年龄段中各证型分布比较,差异有统计学意义(χ~2=72.710,P=0.000)。CD4+T细胞计数不同分层中各证型分布比较,差异有统计学意义(χ~2=66.778,P=0.000)。血液途径感染以肾虚髓减证、气虚血瘀证为主,性途径感染以肝肾阴虚证为主。结论 CD4+T细胞计数分层、年龄段、病情程度和感染途径会影响ADC证型分布。Objective To study the relationship between different syndromes of AIDS dementia complex(ADC)and different disease severity,age,CD4+T cell count and infection.Methods Totally186patients with ADC wereclassified into different syndrome types,and the distribution in different degree of disease,different age,differentCD4+T cell count and different routes of infection was analyzed.Results There were48,51,15,37and35cases ofdeficiency of kidney and marrow,yin deficiency of liver and kidney,deficiency of heart and spleen,syndrome ofphlegm obstruction,syndrome of qi deficiency and blood stasis,respectively.Moderate and severe degrees with yindeficiency of liver and kidney were more common.There was statistical significance in the distribution of differentsyndromes in different degree of disease(χ2=82.495,P=0.000).Deficiency of kidney and marrow,yin deficiency of liverand kidney were more common in different age groups.The distribution of the syndrome types in different age groups wasstatistically significant(χ2=72.710,P=0.000),the patients were mainly in two age groups of>50–60years old and>60years old.The distribution of the syndrom types in diffenrent CD4+T cell count stratum was statistically significant(χ2=66.778,P=0.000).Blood pathway infection mainly included deficiency of kidney and marrow and syndrome ofqi deficiency and blood stasis,sexual pathogens mainly yin deficiency of liver and kidney.Conclusion CD4+T cellslayers,age group,progression of disease and transmission way are the influencing factors of syndrom type.

关 键 词：艾滋病痴呆复合征 中医证型 

分 类 号：R259.933[医药卫生—中西医结合]