热毒清口服液质量控制方法的改进  

Improvement of Quality Standard of Reduqing Oral Liquid

作　　者：王盛[1,2] 陈莉[1,2] 冯艺戎[1,2] 蔡敏[1] WANG Sheng;CHEN Li;FENG Yi-rong;CAI Min(The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031,China;State Administration of National Chinese Drugs Medicament Laboratory of Grade 3, Hefei 230031, China)

机构地区：[1]安徽中医药大学第一附属医院,安徽合肥230031 [2]国家中医药管理局中药制剂三级实验室,安徽合肥230031

出　　处：《中国中医药信息杂志》2017年第3期75-77,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：安徽省卫生厅中医药科研课题(2012ZY20)

摘　　要：目的改进热毒清口服液的质量标准。方法采用薄层色谱法对方中的甘草、射干、黄芩进行鉴别;采用高效液相色谱法测定热毒清口服液中黄芩苷的含量。结果薄层色谱法能够鉴别出甘草、射干、黄芩的特征斑点;黄芩苷在53.60~536.00μg/m L范围内呈良好的线性关系(r=0.999 99),平均加样回收率为99.85%,RSD=0.63%(n=6)。结论本方法操作简单,准确可靠,可有效控制热毒清口服液的质量。Objective To improve the quality standard of Reduqing Oral Liquid.Methods TLC was used toidentify the featured spots of Glycyrrhizae Radix et Rhizoma,Belamcandae Rhizoma and Scutellariae Radix;HPLCmethod was usded to detect the contents of Baicalin in Reduqing Oral Liquid.Results TLC could identify the featuredspots of Glycyrrhizae Radix et Rhizoma,Belamcandae Rhizoma and Scutellariae Radix;Baicalin was detected inrange of53.60–536.00μg/mL with good linear relationship(r=0.99999),the average recovery rate was99.85%,andRSD was0.63%(n=6).Conclusion The method is simple,accurate and reliable,which can be applied to the qualitycontrol of Reduqing Oral Liquid.

关 键 词：热毒清口服液 薄层色谱法 高效液相色谱法 质量控制 

分 类 号：R284.1[医药卫生—中药学]