胰十二指肠切除术吻合器的制备与性能  

Preparation and Properties of Anastomat for Pancrea ticod u odenectomy

作　　者：张亮[1] 李颖[2] 马峰[1] ZHANG Liang;LI Ying;MA Feng(Bidding and Purchasing Office, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an Shaanxi 710061, China;Department of Material Science and Engineering, Xi’an University of Science and Technology, Xi’an Shaanxi 710054,China)

机构地区：[1]西安交通大学第一附属医院招采办,陕西西安710061 [2]西安科技大学材料科学与工程学院,陕西西安710054

出　　处：《中国医疗设备》2017年第2期24-27,42,共5页China Medical Devices

基　　金：陕西省教育厅科研计划项目资助项目(2013JK0920);西部地区人才培养特别项目(留金法[2014]5049;201408615042)

摘　　要：为了有效阻止胰十二指肠切除术中的胰液渗漏,本研究以甲基乙烯基硅橡胶为主要原料,研制出可用于临床应用的吻合器。该吻合器基体为硅橡胶,添加硫化剂和补强填料等助剂,埋入钛钉,一次硫化成型胰肠吻合器,并对其耐热性、力学性能、耐介质性及病理学进行测试分析。结果表明,吻合器质量损失5%时所对应的温度为429.9℃,经历280℃×6 h的热空气,其断裂伸长率和拉伸强度仅下降了25.6%和2.3%,经过蒸馏水、3%双氧水,75%酒精、盐酸(p H=0.8)和氢氧化钠(p H=9)介质浸泡的吻合器质量损失最大仅为5.63%;吻合器可促使胰腺与肠壁之间纤维组织的增生,实现十二指肠和胰腺正常的血液循环,为降低手术难度、缩短手术时间及提高手术成功率奠定试验基础。In order to effectively prevent the leakage of the pancreatic fluid during pancreati cod uode nectomy, this study took methyl vinyl silicone rubber as main material and prepares a pancreaticojejunostomy anastomat for clinical application. Through one step vulcanization molding with pre-embedded titanium nails, using silicone rubber as matrix, adding vulcanizing agent and reinforcingfilling, etc., the thermal property, mechanical property and chemical resistance property of the anastomat were analyzed. Results showed that when quality loss was 5%, the corresponding temperature ofanastomat was 429.9℃. The breaking elongation rate and tensile strength decreased only 25.6% and2.3% after enduring in 280℃ hot air for 6 h. The maximum quality loss was only 5.63% after soaking inthe distilled water, 3% dioxygen water, 75% alcohol, hydrochloric acid (pH=0.8) and sadium hydroxide solution (pH=9) respectively. By using pancreaticojejunostomy anastomat, the fibrin hyperplasia betweenpancreas and intestinal wall will be promoted, normal blood circulation of duodenum and pancreas willalso be enhanced, thus established the experimental basis for reducing operation difficulty, shortening surgery time and achieving high operative success rate.

关 键 词：胰十二指肠切除术 硅胶胰肠吻合器 一次硫化成型 耐热性分析 耐介质性分析 

分 类 号：TH779[机械工程—仪器科学与技术]