阻塞性睡眠呼吸暂停低通气综合征合并注意缺陷多动障碍对睡眠及生活质量的影响  

Effect of pediatric obstructive sleep spnea hypopnea syndrome with attention deficit hyperactivity disorder on sleep and quality of life

作　　者：吴佳欐[1] 顾美珍[1] 陈淑梅[1] 陈伟[1] 倪坤[1] 徐宏鸣[1] 李晓艳[1] WU Jiali;GU Meizhen;CHEN Shumei;CHEN Wei;NI Kun;XU Hongmin;LI Xiaoyan(Department of Otolaryngology &Head and Neck Surgery, Shanghai children’s Hospital, Shanghai Jiaotong University, Shanghai 200040,China)

机构地区：[1]上海交通大学附属儿童医院上海市儿童医院耳鼻喉头颈外科,上海200062

出　　处：《临床儿科杂志》2017年第2期98-101,共4页Journal of Clinical Pediatrics

基　　金：上海市儿童医院院级课题科研基金资助项目(No.2012M013)

摘　　要：目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患儿合并注意缺陷多动障碍(ADHD)的睡眠及生活质量。方法选择2014年1月至2014年12月因OSAHS住院的437例患儿。根据有无合并ADHD,分为单纯组(无ADHD)和合并症组(合并ADHD),比较两组患儿的一般情况以及OSA-18生活质量评分、睡眠监测情况。结果入选的437例OSAHS患儿中男298例,女139例。合并症组147例(33.64%),单纯组291例。合并症组的呼吸暂停低通气指数(AHI)较单纯组更高,最低氧饱和度(LSa O2)也更低,差异均有统计学意义(P<0.01);合并症组的OSA-18生活质量5项评分均高于单纯组,生活质量更差,差异均有统计学意义(P<0.01)。结论 OSAHS患儿合并ADHD的发病率高达30%以上,男性居多,缺氧更严重,生活质量更差。Objective Related factors of pediatric obstructive sleep apnea hypopnea syndrome (OSAHS) combined with attention deficit hyperactivity disorder (ADHD) were retrospectively analyzed in OSAHS children. Methods The research included 437 cases of children hospitalized for OSAHS from January, 2014 to December, 2014. All the cases were divided into OSAHS group and OSAHS combined with ADHD group, according to the presence or absence of ADHD. Patient's general conditions (gender, age, height, weight, allergic rhinitis history, tonsil grade and adenoid grade), OSA-18 quality of life score,intention-hyperactivity score, polysomnography parameter (apnea hypopnea index, lowest oxygen) were collected as variables.SPSS20.0 was used to perform statistical analyses. Results There were 437 cases in this research, 298 of them were males, and139 of them were females. Of 437 patients, 147 had OSAHS combined with ADHD (33.64%). Higher apnea hypopnea index(P < 0.01) and severer oxygen deficiency (P < 0.01) were found in OSAHS combined with ADHD group than those in OSAHA group. Five projects of OSA - 18 score of in OSAHS combined with ADHD group were all higher than those in OSAHS group (P < 0.01). Conclusions The incidence of pediatric OSAHS combined with ADHD in this research was more than 30%. More OSAHS combined with ADHD were found in male children. The quality of life was lower in pediatric OSAHS combined with ADHD. Oxygen deficiency was suggested to be the most important risk factor of ADHD in pediatric OSAHS.

关 键 词：注意缺陷多动障碍 阻塞性睡眠呼吸暂停低通气综合征 缺氧 儿童 

分 类 号：R766[医药卫生—耳鼻咽喉科] R749.94[医药卫生—临床医学]