甲硝唑与奥硝唑治疗宫颈糜烂的疗效及对免疫球蛋白、炎性细胞因子的影响分析  

Analysis of the curative effect of metronidazole and ornidazole in the treatment of cervical erosion and the influence of immunoglobulin and inflammatory cytokines

作　　者：宋洁 提爱军[2] Song Jie;Ti Aijun(Tushan Town Health Center of Laizhou City,Shandong Province 261413;Laizhou City People's Hospital of Shandong Province 261400)

机构地区：[1]山东省莱州市土山镇卫生院,261413 [2]山东省莱州市人民医院,261400

出　　处：《中国社区医师》2017年第8期67-68,共2页Chinese Community Doctors

摘　　要：目的:探讨甲硝唑与奥硝唑治疗宫颈糜烂的疗效及对免疫球蛋白、炎性细胞因子的影响。方法:收治宫颈糜烂患者160例,随机分成A、B两组,各80例。两组均给予微波治疗,A组在此基础上给予奥硝唑,B组给予甲硝唑,比较两组的疗效,检测治疗前后免疫球蛋白和炎性细胞因子水平。结果:A组总有效率为96.3%,B组为87.5%,差异具有统计学意义(P<0.05)。治疗后两组炎性细胞因子明显减少,A组炎性细胞因子更少。结论:甲硝唑和奥硝唑均可降低炎性细胞因子水平,相较于甲硝唑,奥硝唑在宫颈糜烂中的疗效更佳。Objective:To explore the curative effect of metronidazole and ornidazole in the treatment of cervical erosion and the influence of immunoglobulin and inflammatory cytokines.Methods:160patients with cervical erosion were selected.They were randomly divided into two groups,and the two groups were treated with microwave treatment.The A group was given ornidazole on this basis,and the B group was given metronidazole.The curative effects of two groups were compared.The immunoglobulin and inflammatory cytokines levels were detected before and after treatment.Results:The total effective rate of the A group was96.3%,the total effective rate of the B group was87.5%,and the difference was statistically significant(P<0.05).After treatment,the inflammatory cytokines in the two groups were significantly decreased,and the inflammatory cytokines of the A group were lower.Conclusion:Metronidazole and ornidazole can reduce the level of inflammatory cytokines.Compared with metronidazole,the curative effect of ornidazole is better in the treatment of cervical erosion.

关 键 词：甲硝唑 奥硝唑 宫颈糜烂 免疫球蛋白 炎性细胞因子 

分 类 号：R711.32[医药卫生—妇产科学]