火绒草的苯丙素类成分  

Phenylpropanoids from Lentopodium lenotopodioides

作　　者：肖阳央 苟萍[3] 谢海辉[1] XIAO Yang-yang;GOU Ping;XIE Hai-hui(Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China;University of Chinese Academy of Sciences, Beijing 100049,China;College of Life Science and Technology, Xinjiang University, Urumqi 830046, China)

机构地区：[1]中国科学院华南植物园,广东省应用植物学重点实验室,广州510650 [2]中国科学院大学,北京100049 [3]新疆大学生命科学与技术学院,乌鲁木齐830046

出　　处：《热带亚热带植物学报》2017年第2期195-201,共7页Journal of Tropical and Subtropical Botany

基　　金：国家自然科学基金面上项目(31460081)资助~~

摘　　要：采用含水乙醇提取、三氯甲烷脱色、正丁醇萃取和多种色谱分离方法,从新疆产菊科植物火绒草(Lentopodium lenotopodioides)全草中获得8个苯丙素类化合物。通过波谱数据分析,分别鉴定为二氢去氢二松柏醇4-O-β-D-葡萄糖苷(1)、二氢去氢二松柏醇9′-O-β-D-葡萄糖苷(2)、去氢二松柏醇9′-O-β-D-葡萄糖苷(3)、去氢二松柏醇9′-甲醚-4-O-β-D-葡萄糖苷(4)、(-)-松脂醇4-O-β-D-葡萄糖苷(5)、(-)-杜仲树脂酚4-O-β-D-葡萄糖苷(6)、枸橼苦素C(7)和咖啡酸(8)。化合物2~7为首次从该植物中报道。在500μmol L^(-1)浓度下,这些化合物对α-葡萄糖苷酶的抑制率均低于50%。In order to understand the chemical constituents from Lentopodium lenotopodioides(Asteraceae),eight phenylpropanoids were obtained from its whole herbs by multiple chromatographic separation techniques.On the basis of spectral data,their structures were identified as dihydrodehydrodiconiferyl alcohol4-O-β-D-glucoside(1),dihydrodehydrodiconiferyl alcohol9′-O-β-D-glucoside(2),dehydrodiconiferyl alcohol9′-O-β-D-glucoside(3),dehydrodiconiferyl alcohol9′-methyl ether-4-O-β-D-glucoside(4),(?)-pinoresinol4-O-β-D-glucoside(5),(?)-medioresinol4-O-β-D-glucoside(6),citrusin C(7),and caffeic acid(8).Compounds2-7were obtained from this species for the first time.The inhibitory rates of these compounds towardα-glucosidase were less than50%at the concentration of500μmol L?1.

关 键 词：火绒草 木脂素类 枸橼苦素C 咖啡酸 α-葡萄糖苷酶抑制活性 

分 类 号：R284[医药卫生—中药学]