瓜蒌及其炮制品红外光谱分析  

Infrared Spectrum Analysis on Trichosanthes kirilowii Maxim and Its Processed Products

作　　者：宗倩妮 王静 徐启祥 邹纯才[1] 鄢海燕[1] Zong Qianni;Wang Jing;Xu Qixiang;Zou Chuncai;Yan Haiyan(College of Pharmacy, Wannan Medical College, Wuhu, Anhui 241002, China)

机构地区：[1]皖南医学院药学院,安徽芜湖241002

出　　处：《大理大学学报》2017年第2期24-30,共7页Journal of Dali University

基　　金：安徽高校省级自然科学研究基金资助项目(KJ2015ZD41;KJ2016SD60);安徽省科技攻关基金资助项目(12010402089)

摘　　要：目的:分析炮制对瓜蒌主要化学成分类别的影响。方法:通过对瓜蒌及其炮制品红外图谱的比较,分析炮制对瓜蒌主要化学成分类别的影响,并推断出其主要成分。结果:瓜蒌及其炮制品一阶导数IR图谱较为相似。在1 240 cm^(-1)附近都含有δOH;在3 300~3 420 cm^(-1)处都含有黄酮类或糖类、苷类或醇类物质的vOH;2 853~2 930 cm^(-1)有甲基或亚甲基的vCH;在1 510~1 660 cm^(-1)都含有蛋白质N-H的δNH或芳香类物质苯环的vC-C;在1 050 cm^(-1)附近都含有黄酮或多糖、苷的vC-O。瓜蒌及其炮制品二阶导数IR图谱指纹性较强,可用于区分瓜蒌及其炮制品。结论:瓜蒌炮制前后化学成分类别变化不大,二阶导数IR图谱可更好地用于瓜蒌及其炮制品的鉴别。Objective: To analyze the influence of processing methods on chemical constituents in Trichosanthes kirilowii Maxim.Methods: The chemical differences of Trichosanthes kirilowii Maxim before and after processing were analyzed by Fourier Transform Infrared Spectrum(FTIR)and the main chemical composition was identified. Results: Infrared spectra of Trichosanthes kirilowii Maxim and its processed products were similar. The IR characteristic absorption peaks of certain constituent are found: 1 240 cm- 1(δOH), 3 300-3 420 cm- 1(νOH of flavonoids and polysaccharide, glycosides, or alcohol O-H), 2 853-2 930 cm- 1(νCH of methyl or methylene C-O)and 1 510-1 660 cm-1(δNH of protein N-H or νC-C of aromatic compounds benzene ring)and 1 050 cm-1(flavonoids or νC- O of polysaccharide and glycosides). The second derivative spectra of Trichosanthes kirilowii Maxim and its processed products revealed more fingerprint peaks, which helps to separate Trichosanthes kirilowii Maxim and its processed products. Conclusion: The chemical composition of Trichosanthes kirilowii Maxim had little changes after the processing procedure, and the second derivative spectra offered better identification of Trichosanthes kirilowii Maxim and its processed products.

关 键 词：瓜蒌 炮制 红外光谱 

分 类 号：O657[理学—分析化学]