急性心肌梗死采用血栓抽吸联合抗栓治疗的临床效果  

Clinical effect of acute myocardial infarction treated with thrombus aspiration combined with antithrombus therapy

作　　者：刘艳[1] 智永超[1] LIU Yan;ZHI Yong-chao(Department of Cardiology, Dalian City Central Hopsital,Dalian 116033, China)

机构地区：[1]大连市中心医院心内科,116033

出　　处：《中国现代药物应用》2017年第5期81-83,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探究急性心肌梗死采用血栓抽吸与抗栓治疗的效果和安全性。方法 48例急性心肌梗死患者,随机分为治疗组和对照组,各24例。对照组采用抗栓治疗,治疗组采用血栓抽吸联合抗栓治疗,观察分析两组患者的治疗效果,各项指标改善情况[慢血流/无复流发生率、治疗后TIMI血流分级0~1级、术后1 h ST回落良好率、左心室舒张末径(LVEDD)、左心室射血分数(LVEF)和术后1个月内主要不良心脏事件(MACE)累积发生率]和不良反应发生率。结果治疗组的治疗总有效率为91.67%高于对照组的66.67%,差异有统计学意义(P<0.05)。治疗组的术后1 h ST回落良好率、LVEDD、LVEF优于对照组,差异有统计学意义(P<0.05);两组治疗后TIMI血流分级0~1级、慢血流/无复流发生率、术后1个月内MACE累积发生率比较差异无统计学意义(P>0.05)。治疗组的不良反应发生率为8.33%低于对照组的33.33%,差异有统计学意义(P<0.05)。结论采用血栓抽吸联合抗栓治疗急性心肌梗死患者具有较大的意义,值得信赖。Objective To explore the effect and security of acute myocardial infarction treated with thrombus aspiration combined with antithrombus therapy. Methods A total of 48 acute myocardial infarction patients were randomly divided into treatment group and control group, with 24 cases in each group. The control group received antithrombus therapy and the treatment group received hrombus aspiration combined with antithrombus therapy. Observation and analysis were made on treatment effect, indexes improvement[incidence of slow flow/no reflow, TIMI flow grade 0~1 after treatment, ST down good rate in postoperative 1 h,left ventricular end-diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF) and incidence of major adverse cardiovascular events (MACE) cumulative in postoperative 1 month] and incidence of adverse reactions in two groups. Results The treatment group had higher total treatment effective rate as 91.67% than 66.67% in the control group, and the difference had statistical significance (P<0.05). The treatment group had better ST down good rate in postoperative 1 h, LVEDD and LVEF than the control group, and the difference had statistical significance (P<0.05). After treatment, there was no statistically significant difference of TIMI flow grade 0~1,incidence of slow flow/no reflow, and cumulative incidence of MACE in postoperative 1 month between the two groups (P>0.05). The treatment group had lower incidence of adverse reactions as 8.33% than 33.33% in the control group, and the difference had statistical significance (P<0.05). Conclusion Combination of thrombus aspiration and antithrombus therapy provides great significance for the treatment of acute myocardial infarction,and it is trustworthy.

关 键 词：急性心肌梗死 血栓抽吸 抗栓治疗 临床效果 

分 类 号：R542.22[医药卫生—心血管疾病]