天然高分子衍生材料在骨组织修复领域的研究进展  

Research progress of natural polymer derived materials in bone tissue repair

作　　者：冯星龙 王晓岚[2] 张余[2] 夏虹[2] FENG Xinglong;WANG Xiaolan;ZHANG Yu;XIA Hong(Department of Traumatology & Burn, Central Hospital of Panyu District, Guangzhou, Guangdong 511400, China)

机构地区：[1]广州市番禺区中心医院创伤烧伤科,511400 [2]广州军区广州总医院骨科医院广东省骨科矫形技术与植入材料重点实验室,510010

出　　处：《中国骨科临床与基础研究杂志》2017年第1期45-49,共5页Chinese Orthopaedic Journal of Clinical and Basic Research

基　　金：国家自然科学基金(21620102004)

摘　　要：天然高分子衍生材料具有良好的生物相容性、可降解性和一定的成骨诱导能力,是骨替代材料的潜在发展方向之一。本文主要介绍胶原蛋白及明胶等胶原材料、丝蛋白、甲壳素及其衍生物、海藻酸盐等天然高分子衍生材料的特点、功能及其在骨组织修复领域的研究成果,同时对其应用前景进行展望。With good biocompatibility,degradability and certain osteogenic induction ability,naturalpolymer derived material has become one of the potential development directions in the field of bone substitutematerials.In this paper,we mainly introduced the characteristics and functions of natural macromoleculematerials such as collagen materials(collagen protein,gelatin,etc.),silk protein,chintin and its derivatives,aswell as alginates,more importantly,we discussed the current progresses and the application prospects of thesenew materials in bone tissue repair.

关 键 词：胶原 丝蛋白 壳多糖 藻酸盐 骨代用品 生物相容性材料 

分 类 号：R318.08[医药卫生—生物医学工程] R687[医药卫生—基础医学]