左西替利嗪、曲尼司特联合卡介苗素治疗慢性荨麻疹的临床效果观察  

Observation of the clinical effect of levocetirizine, tranilast combined with BCG therapy in chronic urticaria

作　　者：曹忠琛 CAO Zhong-chen(Department of Pharmacy, Jining City, Shandong 272100,China)

机构地区：[1]济宁市皮肤病防治院药剂科,山东济宁272100

出　　处：《中国处方药》2017年第4期1-2,共2页Journal of China Prescription Drug

摘　　要：目的探究左西替利嗪、曲尼司特联合卡介苗素(BCG)治疗慢性荨麻疹的临床效果。方法本次研究对象从2014年12月~2016年8月在院就诊的慢性荨麻疹患者中选取98例,通过动态化随机分组的方法将其分为2组,对照组患者采用左西替利嗪进行治疗,观察组患者采用左西替利嗪、曲尼司特联合卡介苗素进行治疗,探究经不同方法治疗后治疗效果、复发率以及不良反应发生率的差异性。结果观察组患者的治疗效果明显优于对照组患者,且复发率以及不良反应发生率明显低于对照组患者,差异均具有统计学意义(P<0.05)。结论左西替利嗪、曲尼司特联合卡介苗素治疗慢性荨麻疹具有一定的治疗效果,可以有效降低患者的复发几率,安全有效。Objective To observe the clinical effect of levocetirizine, tranilast combined with BCG therapy in chronic urticaria. Methods From December 2014 to August 2016,98 cases of patients with chronic urticaria in hospital were selected as objects and divided into two groups by dynamic randomization methods. The control group were treated with levocetirizine, and the observation group were treated with levocetirizine, tranilast joint BCG treatment. Then to explore the clinical effect,relapse rate and adverse reaction rates differences in different methods of treatment after treatment. Results Clinical total effective rate, relapse rate and incidence of adverse events of observation group were significantly better than the control group patients(P < 0.05). Conclusion The therapy of levocetirizine, tranilast combined with BCG in chronic urticaria has a therapeutic effect, can effectively reduce the risk of recurrence in patients with safe, effective.

关 键 词：左西替利嗪 曲尼司特 卡介苗素 慢性荨麻疹 临床效果 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]