阿司匹林联合丙种球蛋白治疗小儿川崎病效果观察  

Effect observation of aspirin combined with gamma globulin in the treatment of Kawasaki disease in children

作　　者：何逾祥[1] HE Yu-xiang(Department of Pediatrics, Foshan City First Poeple’s Hospital, Foshan 528000, China)

机构地区：[1]佛山市第一人民医院儿科,528000

出　　处：《中国现代药物应用》2017年第6期93-94,共2页Chinese Journal of Modern Drug Application

摘　　要：目的观察阿司匹林联合丙种球蛋白治疗小儿川崎病效果。方法 40例小儿川崎病患儿,按数字随机表分为对照组(19例)和研究组(21例)。对照组采用阿司匹林治疗,研究组采用阿司匹林联合丙种球蛋白治疗。对比两组皮疹消退、发热消退、结膜充血消退、淋巴结肿大消退时间及治疗效果。结果研究组皮疹消退、发热消退、结膜充血消退及淋巴结肿大消退时间短于对照组,差异具有统计学意义(P<0.05)。研究组总有效率95.24%明显高于对照组的68.42%,差异具有统计学意义(P<0.05)。结论小儿川崎病采用阿司匹林联合丙种球蛋白治疗,疗效较佳,症状在短时间内得到缓解,建议推广。Objective To observe the effect of aspirin combined with gamma globulin in the treatment of Kawasaki disease in children.Methods A total of40children with Kawasaki disease were divided by random number table into control group(19cases)and research group(21cases).The control group received aspirin for treatment,and the research group received aspirin combined with gamma globulin for treatment.Comparison were made on rash,fever,conjunctival congestion and lymph node enlargement regression time and treatment effect in two groups.Results The research group had shorter rash,fever,conjunctival congestion and lymph node enlargement regression time than the control group,and the difference had statistical significance(P<0.05).The research group had obviously higher total effective rate as95.24%than68.42%in the control group,and the difference had statistical significance(P<0.05).Conclusion Combination of aspirin and gamma globulin shows good curative effect in the treatment of Kawasaki disease,and symptoms are remitted in a short time,it is recommended for promotion.

关 键 词：小儿川崎病 阿司匹林 丙种球蛋白 治疗 

分 类 号：R725.4[医药卫生—儿科]