超声内镜在消化道间叶源性肿瘤诊断的价值研究  

The value of endoscopic ultrasonography in the diagnosis of gastrointestinal stromal tumors

作　　者：聂胜利[1] 王蓓蓓[1] 张庆芳[1] 吴军辉[1] Nie Shengli;Wang Beibei;Zhang Qingfang;Wu Junhui(Department of Gastroenterology, Guangdong Academic of Medical Sciences, Guangdong General Hospital, Institute of Geriatrics, Guangzhou 510080, China)

机构地区：[1]广东省人民医院(广东省医学科学院)消化科,广州510080

出　　处：《中华结直肠疾病电子杂志》2017年第2期114-116,共3页Chinese Journal of Colorectal Diseases(Electronic Edition)

摘　　要：目的探讨超声内镜在消化道间叶源性肿瘤诊断的价值。方法选取广东省人民医院进行常规内镜检查并经超声内镜确诊为消化道间叶源性肿瘤且具有完整的病理学资料的130例患者进行回顾性分析总结,比较超声内镜和病理学检测以及免疫组化研究的差异。结果 130例患者中进行病理和免疫组织化学检查的患者101例,超声内镜诊断的消化道叶源性肿瘤有平滑肌瘤、间质瘤以及脂肪瘤,96例患者的超声内镜与病理及免疫组化得到的结果一致;病灶多位于食道和胃部;超声内镜的灵敏度、特异度、估计准确率较高,其中超声内镜对脂肪瘤诊断的敏感度、特异度、阳性和阴性预测值均为100.00%;对间质瘤和平滑肌瘤诊断的敏感度、特异度、阳性和阴性预测值分别为100.00%vs 85.00%,82.61%vs 95.24%,68.18%vs 72.00%,100.00%vs 96.29%。结论超声内镜在消化道间叶源性肿瘤诊断中具有较高的准确率,可在临床中逐步推广。Objective To evaluate the value of endoscopic ultrasonography in the diagnosis ofmesenchymal tumors in the digestive tract.Methods A total of130patients with complete endoscopicultrasonography and endoscopic diagnosis of gastrointestinal mesenchymal tumors with complete pathologicdata were retrospectively analyzed.Differences in ultrasound endoscopy,pathology and immunohistochemistrywere compared.Results Of the130patients,101patients underwent pathology and immunohistochemistry.Gastronintestinal mesenchymal tumors were leiomyoma,stromal tumors,and lipomas.Ultrasound endoscopyin96patients was consistent with the results obtained by pathology and immunohistochemistry.Lesions werelocated in the esophagus and stomach.The sensitivity,specificity,estimated accuracy of ultrasound endoscopicis higher.The sensitivity,specificity,positive and negative predictive value of endoscopic ultrasonography in thediagnosis of lipoma were100.00%.The sensitivity,specificity,positive and negative predictive values for thediagnosis of stromal tumors and leiomyoma were100.00%vs85.00%,82.61%vs95.24%,68.18%vs72.00%,100.00%vs96.29%.Conclusion Ultrasound endoscopy in the diagnosis of mesenchymal tumors in thedigestive tract has a high accuracy,can be gradually extended in clinical practice.

关 键 词：超声内镜 诊断 消化道间叶源性肿瘤 

分 类 号：R445.1[医药卫生—影像医学与核医学] R735[医药卫生—诊断学]