Diabetic foot disease:From the evaluation of the “foot at risk” to the novel diabetic ulcer treatment modalities  

作　　者：Noha Amin John Doupis 

机构地区：[1]Department of Internal Medicine (Diabetes and Metabolism Unit), Alexandria University [2]Iatriko Paleou Falirou Medical Center, Division of Diabetes and Clinical Research Center [3]Postgraduate Diabetes Education, Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine

出　　处：《World Journal of Diabetes》2016年第7期153-164,共12页世界糖尿病杂志（英文版）（电子版）

摘　　要：The burden of diabetic foot disease(DFD) is expected to increase in the future. The incidence of DFD is still rising due to the high prevalence of DFD predisposing factors. DFD is multifactorial in nature; however most of the diabetic foot amputations are preceded by foot ulceration. Diabetic peripheral neuropathy(DPN) is a major risk factor for foot ulceration. DPN leads to loss of protective sensation resulting in continuous unconscious traumas. Patient education and detection of high risk foot are essential for the prevention of foot ulceration and amputation. Proper assessment of the diabetic foot ulceration and appropriate management ensure better prognosis. Management is based on revascularization procedures, wound debridement, treatment of infection and ulcer offloading. Management and type of dressing applied are tailored according to the type of wound and the foot condition. The scope of this review paper is to describe the diabetic foot syndrome starting from the evaluation of the foot at risk for ulceration, up to the new treatment modalities.The burden of diabetic foot disease(DFD) is expected to increase in the future. The incidence of DFD is still rising due to the high prevalence of DFD predisposing factors. DFD is multifactorial in nature; however most of the diabetic foot amputations are preceded by foot ulceration. Diabetic peripheral neuropathy(DPN) is a major risk factor for foot ulceration. DPN leads to loss of protective sensation resulting in continuous unconscious traumas. Patient education and detection of high risk foot are essential for the prevention of foot ulceration and amputation. Proper assessment of the diabetic foot ulceration and appropriate management ensure better prognosis. Management is based on revascularization procedures, wound debridement, treatment of infection and ulcer offloading. Management and type of dressing applied are tailored according to the type of wound and the foot condition. The scope of this review paper is to describe the diabetic foot syndrome starting from the evaluation of the foot at risk for ulceration, up to the new treatment modalities.

关 键 词：DIABETES DIABETIC FOOT DIABETIC ULCER DIABETIC COMPLICATIONS DIABETIC NEUROPATHY DIABETIC macroanggiopathy 

分 类 号：R587.2[医药卫生—内分泌]