不同肥胖亚型对肾功能的影响研究  

Different subtypes of obesity influnce on renal function

作　　者：宁昭哲 张弛[1] 周桂莲[1] 王敏[1] 熊璞[1] 王霞[1] 陈晶[1] 刘瑛[1] 朱艳[1] 王莎[1] 张彩丽[1] Ning Zhaozhe;Zhang Chi;Zhou Guilian;Wang Min;Xiong Pu;Wang Xia;Chen Jing;Liu Ying;Zhu Yan;Wang Sha;Zhang Caili(The First Hospital Affiliated to Hunan Normal University(Department of Endocrinology,the People's Hospital of Hunan Province) 410005)

机构地区：[1]湖南师范大学第一附属医院湖南省人民医院内分泌科,410005

出　　处：《中国社区医师》2017年第12期107-108,共2页Chinese Community Doctors

基　　金：湖南省科技计划基金资助项目(2011SK3160);湖南省保健委重点资助项目(A2009-02);湖南省卫生厅重点基金资助项目(A2007005)~~

摘　　要：目的:探讨不同肥胖亚型对肾功能的影响。方法:收集体检人群并连续随访8年共374例,记录一般情况、相关临床及生化指标。结果:与正常体重、正常代谢人群相比,MHO、肥胖MS人群肌酐水平明显升高(P<0.05),MHO、肥胖伴单个代谢异常、肥胖MS发生肾功能损害的风险增高(P<0.05)。结论:不同亚型肥胖促进肾功能损害的发展,肥胖与代谢异常共同作用于肾功能损害的发展。Objective:To investigate the effects of different subtypes of obesity on renal function.Methods:374physical personwere collected.Followed up for8years,we recorded their general information,clinical and biochemical parameters.Results:Compared with normal weight and normal metabolism population,creatinine levels among MHO and obesity MS person increasedsignificantly(P<0.05),and the renal damage increased in MHO,obesity combined with single metabolic abnormalities,and obesityMS person(P<0.05).Conclusion:Different subtypes of obesity contribute to the development of renal dysfunction.Obesity andmetabolic abnormalities contribute to the development of renal dysfunction.

关 键 词：肥胖 炎性因子 肾功能 

分 类 号：R589.2[医药卫生—内分泌]