有无明显诱因导致早产合并胎膜早破对母儿的影响研究  

Research of influence by preterm premature rupture of membranes with or without obvious inducement on mother and infant

作　　者：叶丹 杜玮[2] YE Dan;DU Wei(Panyu District Hexian Memorial Hospital, Guangzhou 511400, China)

机构地区：[1]番禺区何贤纪念医院,511400 [2]广州军区总医院

出　　处：《中国现代药物应用》2017年第7期34-36,共3页Chinese Journal of Modern Drug Application

基　　金：一个是炎性蛋白因子人五聚素3PTX3在因胎膜早破及伴宫内感染致早产中的预测性价值研究(项目编号:2011-Z-03-18)

摘　　要：目的分析有无明显诱因导致早产合并胎膜早破(PPROM)对母儿的影响。方法 420例早产合并胎膜早破患者,根据有无明显诱因分为A组(存在明显诱因)和B组(不存在明显性诱因),各210例。对比分析两组患者一般状况、妊娠状况等。结果两组不良孕产史、分娩孕周、年龄方面比较差异具有统计学意义(P<0.05);两组瘢痕子宫、未定期接受检查、产次方面比较差异无统计学意义(P>0.05)。A组剖宫产率为63.81%、阴道顺产率为32.86%,与B组的25.71%、73.33%比较,差异具有统计学意义(P<0.05);两组阴道助产率比较差异无统计学意义(P>0.05)。A组羊膜腔感染率9.52%明显高于B组的0,差异具有统计学意义(P<0.05);两组胎盘早剥、脐带脱垂率比较差异无统计学意义(P>0.05)。A组新生儿窒息率为11.43%、新生儿体重为(1952.1±632.1)g,与B组的5.71%、(2285.4±595.1)g比较,差异具有统计学意义(P<0.05);两组新生儿畸形率、围生儿死亡率比较差异无统计学意义(P>0.05)。结论存在明显诱因的早产合并胎膜早破患者,母儿存在较高患病可能性,以往孕产史不良、孕妇年龄等情况均和妊娠结局存在关系,临床需针对各病因,给予相应处理措施,降低母儿并发症发生率。Objective To analyze influence by preterm premature rupture of membranes(PPROM)withor without obvious inducement on mother and infant.Methods A total of420patients with preterm premature rupture of membranes were divided by whether with obvious inducement or not into group A(with obvious inducement)and group B(without obvious inducement),with210cases in each group.Comparative analysis was made on general condition and gestation condition between the two groups.Results The difference of adverse pregnancy history,delivery gestational weeks,and age had statistical significance between the two groups(P<0.05).There was no statistically significant difference of scarred uterus,irregular examination and parity between the two groups(P>0.05).Group A had cesarean section rate as63.81%and vaginal eutocia rate as32.86%,which were25.71%and73.33%in group B,and their difference had statistical significance(P<0.05).The difference of vaginal instrumental delivery rate had no statistical significance between the two groups(P>0.05).Group A had obviously higher intraamniotic infection rate as9.52%than0in group B,and the difference had statistical significance(P<0.05).The difference of placental abruption rate and prolapse of cord rate had no statistical significance between the two groups(P>0.05).Group A had neonatal asphyxia rate as11.43%and neonatal birth weight as(1952.1±632.1)g,which were5.71%and(2285.4±595.1)g in group B,and their difference had statistical significance(P<0.05).There was no statistically significant difference of neonatal malformation rate and perinatal mortality between the two groups(P>0.05).Conclusion Preterm premature rupture of membranes with obvious inducement in patients leads to high morbidity in mother and infant.Pregnancy outcome is related with adverse pregnancy history and maternal age.Implement of corresponding treatment measures in accordance with various pathogeny is essential to lower incidence of complications in mother and infant.

关 键 词：孕妇 早产 胎膜早破 妊娠 诱因 明显 

分 类 号：R714.433[医药卫生—妇产科学]