氰霜唑中间体合成工艺研究  

Study on Synthesis of Cyazofamid Intermediate

作　　者：范清华[1] 彭春莲[1] 谭洋[1] 舒展[1] 王超[1] FAN Qinghua;PENG Chunlian;TAN Yang;SHU Zhan;WANG Chao(School of Material Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China)

机构地区：[1]西南科技大学材料科学与工程学院,四川绵阳621010

出　　处：《化工技术与开发》2017年第4期11-12,共2页Technology & Development of Chemical Industry

基　　金：西南科技大学大学生创新基金资助(项目编号CX16-006)

摘　　要：本文通过乌洛托品季铵盐在盐酸乙醇中发生分解反应,合成农药氰霜唑的中间体氨基酮盐酸盐。通过单因素变量法探讨了物料比、反应温度和反应时间对产率的影响,得出反应的最佳条件为:物料比n_(HCl)∶n_(原料)=5.5∶1,反应温度15℃,反应时间24h,纯化后产率可达74.2%。In this article,the intermediate of pesticide cyazofamid,aminoketone hydrochloride,was synthesized by decompositionof quaternary ammonium salt of methenamine in hydrochloric acid/ethanol.The effects of reactant ratio,reaction temperature andreaction time on the reaction yield were studied.To conclude,the optimized conditions were:reactant ratio nHCl:nstarting material=5.5:1,reaction temperature15℃,reaction time24h,and the yield could reach74.2%after purification.

关 键 词：氰霜唑 中间体 氨基酮盐酸盐 

分 类 号：TQ455.47[化学工程—农药化工]