2014-2015年我院质子泵抑制剂应用分析  

Analysis of the application of proton pump inhibitors in our hospital from 2014 to 2015

作　　者：南家林[1] 王小藕[1] 亢卫华[1] NAN Jia-lin;WANG Xiao-ou;KANG Wei-hua(Department of Pharmacy, the Second People's Hospital of Jiaozuo, Jiaozuo 454001,China)

机构地区：[1]焦作市第二人民医院药学部,河南焦作454001

出　　处：《中国药物应用与监测》2017年第2期113-116,共4页Chinese Journal of Drug Application and Monitoring

摘　　要：目的:了解我院质子泵抑制剂(PPIs)使用情况,为临床合理用药提供参考。方法:对我院2014–2015年PPIs品种、金额、用药频度(DDDs)、日均费用(DDC)、使用率等进行统计分析。采取横断面调查的方法,分别抽取两年某天使用PPIs的门诊处方、住院病历,评价其用药合理性。结果:2015年PPIs品规数、金额、DDDs、DDC、使用率、预防应用比例较2014年分别降低了4个、14.22%、2811、4.16、3.66%、7.87%,PPIs临床应用有所改善,不合理用药主要表现在无适应证用药、预防用药疗程偏长与剂量偏大、潜在药物相互作用等问题。结论:我院PPIs仍存在不合理用药现象,应针对问题,制定用药指南,落实药师审方、处方点评与干预,逐步提高临床合理用药水平。Objective:To investigate the usage of proton pump inhibitors(PPIs)in our hospital and provide references for clinical rational use of drugs.Methods:The varieties,consumption sum,DDDs,DDC and the usage ratio of PPIs from2014to2015were analyzed statistically.A cross-sectional investigation was used in the evaluation of PPIs drug rationality,extracting respectively one day of the outpatient prescriptions and inpatient medical records with PPIs in2014and2015.Results:The varieties,consumption sum,DDDs,DDC and the usage ratio of PPIs in2015were respectively reduced4of them,14.22%,2811,4.16,3.66%,7.87%compared with2014.The clinical application of PPIs had been improved.Irrational PPIs use included no-indicationsof medication,slightly long duration and large dosage of the preventive usage,potential drug interactions.Conclusion:There were still many irrational PPIs use in our hospital.To improve the level of clinical rational drug use gradually,we should formulate medication guide,carry out prescription review,prescription comment and intervention.

关 键 词：质子泵抑制剂 用药频度 日均费用 用药分析 

分 类 号：R975[医药卫生—药品]