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作 者:黄仍心 HUANG Reng-xin(Guangdong Province Enping City Maternal and Child Health Care of Family Planning Service Center, Enping 529400, China)
机构地区:[1]广东省恩平市妇幼保健计划生育服务中心,529400
出 处:《中国现代药物应用》2017年第9期154-156,共3页Chinese Journal of Modern Drug Application
摘 要:目的探索护理干预联合鼻塞式持续气道正压通气(NCPAP)治疗新生儿肺透明膜病中的疗效。方法 102例肺透明膜病新生儿,随机分为实验组和对照组,各51例。对照组采用常规鼻塞式NCPAP,实验组在对照组基础上联合护理干预;评价两组治疗前后血氧分压(PaO_2)、二氧化碳分压(PaCO_2)、氧合指数(PaO_2/FiO_2)及呼吸机相关性肺炎发生率、鼻黏膜损伤发生率、住院天数、治疗费用、治疗效果和家属满意度等。结果治疗后,两组PaO_2和PaO_2/FiO_2得到显著提高,PaCO_2有效下降;实验组PaO_2和PaO_2/FiO_2明显高于对照组,PaCO_2显著低于对照组,差异有统计学意义(P<0.05)。实验组呼吸机相关性肺炎、鼻黏膜损伤率、住院天数和治疗费显著低于对照组,差异有统计学意义(P<0.05)。实验组治疗总有效率为84.31%,家属满意度为90.2%高于对照组的66.67%、74.51%,差异有统计学意义(P<0.05)。结论在鼻塞式NCPAP治疗新生儿肺透明膜病中应用护理干预的疗效显著,值得推广。Objective To explore the curative effect of nursing intervention in neonatal hyalinemembrane disease treated with nasal continuous positive airway pressure(NCPAP).Methods A total of102newborns with hyaline membrane disease were randomly divided into experimental group and control group,with51cases in each group.The control group received conventional NCPAP,and the experimental group also receivednursing intervention.Evaluation were made on partial pressure of blood oxygen(PaO2),partial pressure of carbondioxide(PaCO2),oxygenation index(PaO2/FiO2)before and after treatment,ventilator associated pneumonia,incidence of nasal mucosa damage,hospitalization time and therapy cost,treatment effect and satisfaction degreeof family members in two groups.Results After treatment,both groups had significantly increased PaO2andPaO2/FiO2,effectively decreased PaCO2.The experimental group had obviously higher PaO2and PaO2/FiO2thanthe control group,and significantly lower PaCO2than the control group.Their difference had statistical significance(P<0.05).The experimental group had significantly lower ventilator associated pneumonia,incidence of nasalmucosa damage,hospitalization time and therapy cost than the control group,and their difference had statisticalsignificance(P<0.05).The experimental group had higher total treatment effective rate as84.31%and satisfactiondegree of family members as66.67%and74.51%,and their difference had statistical significance(P<0.05).Conclusion Application of nursing intervention shows significant curative effect in neonatal hyaline membranedisease treated with nasal continuous positive airway pressure,and it is worth promotion.
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