药用植物双参正丁醇部位化学成分研究  

Study on Chemical Components from n-butanol Fraction of Medicinal Plants Triplostegia glandulifera

作　　者：陈雅凤 张祖珍 王福生 Chen Yafeng;Zhang Zuzhen;Wang Fusheng(College of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China)

机构地区：[1]大理大学药学与化学学院,云南大理671000

出　　处：《大理大学学报》2017年第4期9-11,共3页Journal of Dali University

基　　金：国家自然科学基金资助项目(31360082)

摘　　要：目的:对药用植物双参正丁醇部位的化学成分进行研究,以期寻找活性成分。方法:运用硅胶、AB-8、ODS以及凝胶等分离材料分离双参正丁醇部位,利用NMR技术鉴定化合物结构。结果:从双参正丁醇部位分离得到5个化合物,分别鉴定为(3S,4R,4a S,6S,7R,7a S)-Methyl 3,6-dihydroxy-7-methyloctahydrocyclopenta[c]pyran-4-carboxylate(1)、咖啡酸甲酯(2)、(+)-Lariciresinol(3)、蔗糖(4)和Alyxialactone(5)。结论:这5个化合物首次从该植物中分离得到,其中,化合物1首次从天然产物中分离得到。Objective:To study the chemical constituents of n-butanol fraction of Triplostegia glandulifera,aiming at searching for active components.Methods:The n-butanol fraction of T.glandulifera was separated by a combination of various chromatographied including silica gel,AB-8,ODS and LH-20gel column chromatography methods,and the structure were identified based on spectroscopic analysis(1H NMR and13C NMR).Results:Five compounds were isolated from T.glandulifera and characterized as(3S,4R,4aS,6S,7R,7aS)-Methyl3,6-dihydroxy-7-methyloctahydrocyclopenta〔c〕pyran-4-carboxylate(1),Methyl caffeate(2),(+)-Lariciresinol(3),Sucrose(4)and Alyxialactone(5).Conclusion:The five constituents were isolated from this genus for the first time,and the compound1was isolated from natural products for the first time.

关 键 词：川续断科 双参 化学成分 

分 类 号：R932[医药卫生—生药学]