硬化参数β结合颈动脉内中膜厚度预测动脉粥样硬化性脑卒中的作用  

Effect of stiffness parameter β combined with carotid intima-media thickness on predicting ischemic stroke

作　　者：蔡叶华[1] 王涌[1] 王怡[1] 陈莉[1] CAI Ye-hua;WANG Yong;WANG Yi;CHEN Li(Department of Medical Ultrasound, Huashan Hospital, Fudan University, Shanghai 200040, China)

机构地区：[1]复旦大学附属华山医院超声医学科,上海200040

出　　处：《上海交通大学学报（医学版）》2017年第5期666-669,共4页Journal of Shanghai Jiao tong University:Medical Science

摘　　要：目的·探索硬化参数β联合颈动脉内中膜厚度(IMT)预测动脉粥样硬化性脑卒中的价值。方法·共99例急性动脉粥样硬化性脑卒中及短暂性脑缺血发作患者纳入研究,经常规颈动脉检查分为IMT增厚组及IMT无增厚组,分别与健康对照组比较其动脉硬化参数β;对IMT无增厚组病例按年龄分层,分别比较各年龄段患者与健康对照组间硬化参数β的差异。结果·(1)IMT增厚组及无增厚组硬化参数β明显高于健康对照组(均P=0.000)。(2)IMT无增厚组按年龄分层后,仅≥60岁年龄组患者的硬化参数β高于健康对照组(左侧P=0.047,右侧P=0.007);而30~39岁、40~49岁及50~59岁年龄组硬化参数β与健康对照组比较,差异均无统计学意义。结论·在≥60岁具有动脉粥样硬化危险因子但无颈动脉IMT增厚及斑块的人群中,IMT结合硬化参数β可提高其预测能力。Objective·To explore whether stiffness parameterβcould help carotid intima-media thickness(IMT)to predict ischemic stroke.Methods·Ninety-nine patients with acute ischemic stroke and transient ischemic attacks were retrospectively evaluated by routine ultrasound and divided into increased IMT group and normal IMT group.The normal IMT group cases were further divided into30～39years,40～49years,50～59years and≥60years groups,and were compared with healthy crowd respectively.Results·①The common carotid artery wallβof both increased IMT group and normal IMT group were significantly higher than healthy crowd(each P=0.000).②Further analysis showed thatβof≥60years group were significantly higher than healthy crowd(left side P=0.047,right side P=0.007);while the difference was not found across younger age groups(30～39years,40～49years and50～59years).Conclusion·Stiffness parameterβmay help carotid intima-media IMT to predict ischemic stroke in high risk subjects≥60years old without morphology changes.

关 键 词：动脉粥样硬化 脑卒中 血管回声跟踪技术 硬化参数 内中膜厚度 

分 类 号：R445.1[医药卫生—影像医学与核医学] R743.3[医药卫生—诊断学]