左西孟旦治疗老年急性心肌梗死后心力衰竭患者的临床疗效  

The Clinical Efficacy of Levosimendan Treatment for Heart Failure after Myocardial Infarction in Patients with Acute Myocardial

作　　者：王晓鹏[1] 秦晓毅[1] 罗根燕 邱银冰[1] 刘国焰[1] WANG Xiao-peng;QIN Xiao-yi;LUO Gen-yan;QIU Yin-bing;LIU Guo-yan(Ganzhou, Jiangxi People's Hospital of Geriatrics, Ganzhou Jiangxi 341000, China)

机构地区：[1]江西省赣州市人民医院老年病科,江西赣州341000

出　　处：《药品评价》2017年第8期39-41,共3页Drug Evaluation

摘　　要：目的:探讨左西孟旦对老年急性心肌梗死后心力衰竭患者的治疗效果。方法:选取2014年10月—2015年9月收治的128例老年急性心肌梗死(Acute myocardial infarction,AMI)后心衰患者按随机数字表法分成观察组和对照组,各64例。对照组患者实行常规治疗措施,观察组在对照组的基础上给予左西孟旦进行治疗。对比两组患者的治疗效果及治疗前、后的炎症反应。结果:观察组治疗的总有效率明显高于对照组(P<0.05);两组治疗前血清炎症因子水平无明显差别(P>0.05);观察组治疗后血清炎症因子水平明显低于对照组(P<0.05)。结论:左西孟旦能有效地提高老年AMI后心力衰竭的治疗效果,并减轻炎症反应。Objective:To investigate the effect of levosimendan treatment of heart failure in patients with acute myocardial infarction(AMI).Methods:128cases of elderly patients with heart failure by AMI in October2014-September2015were randomly divided into observation group and thecontrol group,with64cases in each.The control group patients were with conventional treatment,observation group were given levosimendantreatment on the basis of the control group.Effects and inflammation before treatment and after treatment of two groups were compared.Results:The total efficiency of the observation group was significantly higher(P<0.05);there was no difference in the serum levels of inflammatory factorsbetween two groups(P>0.05);after treatment,serum levels of inflammatory cytokines in the observation group was significantly lower than thecontrol group(P<0.05).Conclusion:Levosimendan can effectively improve the treatment of elderly patients with AMI heart failure,and reduceinflammation.

关 键 词：左西孟旦 老年 急性心肌梗死 心力衰竭 

分 类 号：R541.6[医药卫生—心血管疾病] R542.22[医药卫生—内科学]